Indiana University Purdue University Indianpolis (IUPUI)
Location: Bloomington, Indiana
Internal Number: 15183
Location: IU School of Medicine
Department: IUSM - Medical & Molecular Genetics
Campus: IU School of Medicine Indianapolis
The Department of Medical and Molecular Genetics at Indiana University School of Medicine is seeking applicants at the post-doctoral level for the Post-Doctoral Clinical Genomic Scientist position.
The successful candidates must have a Ph.D. degree with a strong research background in Molecular Genetics. The ideal postdoctoral candidate will analyze and interpret genetic sequence variation identified through diagnostic genetic testing or through research pipelines, primarily using Next Generation Sequencing (WES, WGS, and RNA-seq). In this role, the postdoctoral Clinical Genomics scientist will interpret clinical data, perform phenotype-driven genomic analyses, and maintain an internal database of curated genomics variants. Under the supervision of the URDC (Undiagnosed Rare Disease Clinic) directors, will assist with research projects that report new gene discovery, variant reclassification and lead or contribute to scientific publications.
(*) This position is ideal for individuals who want to gain clinical lab experience before applying to ABMGG Laboratory Genetics and Genomics fellowship training programs, or for those who want to work in clinical molecular diagnostics.
Introduction about your laboratory/unit.
The Undiagnosed and Rare Disease Clinic (URDC) was launched in January 2020. The URDC program combines the strengths of IU Health clinical care specialists and IU School of Medicine researchers. From the clinical side, specialists look through each patients' records, review the list of symptoms, and evaluate each patient when they arrive at the clinic. From the research side, specialists can reevaluate the raw data from a patient's whole exome sequencing test, which involves looking at exons, which are the pieces of an individual's DNA that provide instructions for making proteins. Researchers may also suggest whole genome sequencing to get a better understanding of genetic changes that may lead to health problems. This program is focused mainly on pediatrics, but URDC patients may be any age, from newborns to those with adult-onset disorders, who have likely been seen by multiple providers and had extensive testing done, but still haven't received conclusive results about their condition.
About Indiana University Purdue University Indianpolis (IUPUI)
IUPUI, a partnership between Indiana and Purdue universities, is Indiana’s urban research and academic health sciences campus.
IUPUI’s mission is to advance the state of Indiana and the intellectual growth of its citizens to the highest levels nationally and internationally through research and creative activity, teaching and learning, and civic engagement.
By offering a distinctive range of bachelor’s, master’s, professional, and Ph.D. degrees, IUPUI promotes the educational, cultural, and economic development of central Indiana and beyond through innovative collaborations, external partnerships, and a strong commitment to diversity.