The Department of Neurology at the University of California, Davis, is seeking a full-time Professional Researcher at the Assistant rank to join our growing department. The position will be housed in the Institute for Regenerative Cures in the Gene Therapy Program and as part of the Interventional Genetics Team at UC Davis.
The Professional Researcher develops and oversees his/her own independent, creative, and high-quality research program equivalent to that required for the Professor series. He/she takes major responsibility and leadership for his/her programs. Generally, the appointee is expected to secure funding as a Principal Investigator but may be funded as a co-PI within a large center or collaborative program grant on which many independent investigators are working, as long as it is clear that the activities led by the professional researcher within the larger project constitute his/her own independent research program. Appointees do not have teaching responsibilities.
Research (85%) The candidate is required to develop an independent research program in translational neuroscience.
Devise and conduct studies designed to determine
Lead candidates to successfully regulate and rescue gene function in human and mouse cell models of genetically-linked neurodevelopmental disorders using CRISPR and other gene targeting tools.
Develop disease model systems using both human patient-derived and engineered induced pluripotent stem cells in 2D and 3D neuronal models and to utilize transgenic mice and rats to evaluate in vivo efficacy
Optimal delivery modalities to treat the brain using both AAV gene therapy approaches and engineered stem cells. The candidate will assist in the translation of our gene therapy approaches as part of the larger Gene Therapy Impact Center.
Collect, summarize and analyze data
Publish research results in peer-reviewed journals as first or senior author
Prepare reports on research findings
Acquire funding to support an independent research program
Other activities may include managing the budget and the project; supervising employees paid on the budget; writing and submitting progress reports to funding agencies; and, train, consult with and advise graduate students and postdoctoral researchers with regard to experimental design and data analysis of studies conducted in his or her area of expertise.
Professional Competence (10%) The candidate will participate in professional societies and conferences appropriate to his/her specific field and will serve as a reviewer of research proposals and scientific publications as appropriate. The candidate will attend seminars to present research results and give research presentations at national and international scientific meetings. When appropriate, the candidate may be requested to coordinate seminars and laboratory meetings.
Public Service (5%) Although not required for the Assistant rank, the candidate is encouraged to engage in University service activities such as guest lecturing and committee service. Teaching full classroom courses is not an expectation of this position. The candidate will also engage in public outreach activities that include presenting scientific research results to the general public and providing relevant advice to individuals or public agencies.
UC Davis is the home of the Aggies — go-getters, change makers and problem solvers who make their mark at one of the top public universities in the United States. Since we first opened in 1908, we’ve been known for standout academics, sustainability and Aggie Pride as well as valuing the Northern California lifestyle. These themes are woven into our 100-plus-year history and our reputation for solving problems related to food, health, the environment and society.Our 5,300-acre campus is in the city of Davis, a vibrant college town of about 68,000 located in Yolo County. The state capital is 20 minutes away, and world-class destinations such as the San Francisco Bay Area, Lake Tahoe and the Napa Valley are within a two-hour drive.