There is currently a postdoctoral research scientist position available in Dr. Sproul's laboratory in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain. His lab focuses on human pluripotent stem cell (PSC) models of Alzheimer's disease (AD) in a variety of contexts. Examples of funded projects include development of a human stem-cell derived neurovascular unit system to investigate genetic and age-related risk factors in AD, using pooled CRISPRi/a library screening to identifying AD GWAS hits associated with neuroinflammation, and finding mechanisms of why excitatory neurons are more susceptible to tauopathy than inhibitory neurons. Approaches include CRISPR-mediated genome-editing and gene expression modulation to investigate mechanisms of deleterious and protective genetic factors for AD and the development of novel stem cell differentiation protocols. As these are very collaborative projects with other research groups within the Taub Institute, good communication skills and ability to work well with others are essential for this position.
Conduct research in an independent manner
Lead multiple collaborative projects in parallel
Assist with supervision and guidance of technicians and research assistants
Assist in manuscript and grant writing
Preference will be given to candidates with significant stem cell, vascular, microglial, and/or neuronal culture experience, as well as experience with CRISPR-related technologies.
PhD in a biological discipline with cell culture and molecular biology experience
Applicant must apply on-line and upload current CV.
Hiring Salary Range: $60,000 - $70,000
The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
Columbia University is an Equal Opportunity Employer / Disability / Veteran
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