The Miller Lab at Columbia University Mailman School of Public Health is seeking an Associate Research Scientist with expertise in the field of metabolomics, exposomics, mass spectrometry, or bioinformatics.
The Associate Research Scientist will be responsible for studies utilizing high-resolution mass spectrometry. Duties include organizing and implementing complex research plans, developing research methods and procedures, collecting and analyzing data, and preparing content for manuscripts and publication. Additional duties include the development, implementation, and optimization of the untargeted metabolomics/exposomics platform at the Irving Medical Center Metabolomics Core (CTSA). All research activities will be conducted in accordance to the policies and standard practices of Columbia University.
Design, organize, and conduct highly specialized and advanced experiments using untargeted LC-MS and GC-MC analysis of complex biological samples (40%)
Establish and develop the untargeted workflow using LC-MS and GC-MS (10 %)
Create and customize sample preparation protocol for human (plasma, serum, saliva, urine, other tissue types), cells, and research animals (10 %)
Operate, maintain and troubleshoot mass spectrometry instruments including the GC/LC ThermoFisher Orbitrap MS system (10%)
Follow established and develop new methods for identification and qualification of results/features using standards and/or computational analysis (10%)
Design and implement research protocols; establish safety procedures; design new procedures, methods or instrumentation processes (5%)
Conduct, collect, and analyze research data; create detailed documentation of experiments and research data (10%)
Performs all other duties as assigned (5 %)
A doctoral degree in the appropriate field or the foreign equivalent is required.
Minimum of three years postdoctoral experience in metabolomics/exposomics, mass spectrometry, or bioinformatics.
Experience working with high-resolution mass spectrometry instrumentation.
Expertise using LC-MS and GC-MS in small molecule analysis.
Expertise using bioinformatics tools and statistical software.
Thorough knowledge of the theories, techniques, and methods used in current laboratory assays in the appropriate field.
Ability to communicate effectively both verbally and in writing.
Ability to maintain effective working relationships with supervisors, researchers, staff and other personnel.
Ability to work collaboratively with other research institutions.
Ability to complete all training and certification in compliance with the policies of the Columbia University and federal and state regulations.
Leadership skill is needed to assist staff and other researchers to conduct untargeted metabolomics/exposomics studies. A high level of technical skill is also essential to operate and troubleshoot the mass spectrometry instruments. Strong analytical ability is required to design and perform complex experiments and analyze the data, and to integrate current and new techniques. Ability to instruct staff and technicians on the proper procedures and maintenance of mass spectrometry instruments. Considerable judgment is needed in interpreting data and results, as well as in conducting all research activities in accordance to the guidelines and procedures of Columbia University. Metabolomics/exposomics research and interpretation requires an understanding and application of statistics and computational analysis. A considerable amount of interpersonal and communication skills are necessary to communicate with collaborators.
Hiring Salary Range: $66,100 - $100,000
The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
Columbia University is an Equal Opportunity Employer / Disability / Veteran
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.