The Rubens' Laboratory is seeking a highly motivated Research Specialist to lead the development of new therapeutics targeting metabolic regulation of epigenetic drivers in aggressive pediatric brain tumors. Our laboratory has developed a unique niche in childhood cancer research at the cross-section of drug development, cancer metabolomics, and epigenetics. The Research Specialist will process and analyze metabolomics data, plan and analyze epigenomes sequencing studies, and test the in vitro and in vivo efficacy of novel therapeutics in patient derived cell models and mouse xenografts of pediatric brain tumors. The laboratory exists within the larger Eye and Brain Tumor Research Laboratory in the state-of-the-art Smith Research Building and is part of the Oncology Depart
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