The Rubens' Laboratory is seeking a highly motivated Research Specialist to lead the development of new therapeutics targeting metabolic regulation of epigenetic drivers in aggressive pediatric brain tumors. Our laboratory has developed a unique niche in childhood cancer research at the cross-section of drug development, cancer metabolomics, and epigenetics. The Research Specialist will process and analyze metabolomics data, plan and analyze epigenomes sequencing studies, and test the in vitro and in vivo efficacy of novel therapeutics in patient derived cell models and mouse xenografts of pediatric brain tumors. The laboratory exists within the larger Eye and Brain Tumor Research Laboratory in the state-of-the-art Smith Research Building and is part of the Oncology Department at Johns Hopkins. This position requires experience in basic laboratory techniques in molecular biology and tissue culture.
Specific Duties & Responsibilities
Develops experimental designs and has primary responsibility for planning, implementation, evaluation and interpretation of results; design process may be in collaboration with a post doc, PI, or completed independently.
Identifies problems, troubleshoots and analyzes variations observed and reported in regular testing protocols; modifies, refines or adapts techniques and procedures; modifies and/or adjusts quality control measures.
Coordinates and/or conducts multiple, concurrent assignments or a multi-faceted project.
Compiles, analyzes, and interprets research data, monitors documentation of results; reviews and recognizes documentation, which may lead to modification and adaptation of research methodologies; may collaborate with others; Adapts and/or modifies experimental methods based upon interpretation of data.
Conducts library research and participates in editing and preparing manuscripts, scientific illustrations, and computer graphics for publication.
Oversees and assures laboratory compliance with regulatory requirements and JHU standards, policies and procedures.
Works with research staff to prioritize and schedule projects.
Special Knowledge, Skills & Abilities
Culture and analysis of cell lines, immunohistochemistry, western blot.
Performing established laboratory assays under the supervision of the faculty investigator.
Operation of centrifuge, pH meter, analytical balance, incubator, spectrophotometer, light microscope, imaging systems and laminar flow hoods; Familiarity with aseptic technique.
Familiarity with theory behind experiments; ability to apply analytical skills to interpret experiments using positive and negative controls.
Bachelor's Degree in Biology, Chemistry or related field.
One year of laboratory experience performing relevant techniques.
Master's Degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.
Classified Title: Research Specialist Role/Level/Range: ACRP/03/MA Starting Salary Range: $16.61-$22.83-$29.04 HRLY (Commensurate with experience) Employee group: Full Time Schedule: M-F 8am- 4:30pm Exempt Status: Non-Exempt Location: School of Medicine Campus Department name: SOM Onc Pediatric Oncology Personnel area: School of Medicine
Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines:
*JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
**Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.
The successful candidate(s) for this position will be subject to a pre-employment background check.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the Talent Acquisition Office at firstname.lastname@example.org. For TTY users, call via Maryland Relay or dial 711. For more information about workplace accommodations or accessibility at Johns Hopkins University, please visit accessibility.jhu.edu.
The following additional provisions may apply, depending on campus. Your recruiter will advise accordingly.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
Note: Job Postings are updated daily and remain online until filled.
Johns Hopkins University remains committed to its founding principle, that education for all students should be grounded in exploration and discovery. Hopkins students are challenged not just to learn but also to advance learning itself. Critical thinking, problem solving, creativity, and entrepreneurship are all encouraged and nourished in this unique educational environment. After more than 130 years, Johns Hopkins remains a world leader in both teaching and research. Faculty members and their research colleagues at the university's Applied Physics Laboratory have each year since 1979 won Johns Hopkins more federal research and development funding than any other university. The university has nine academic divisions and campuses throughout the Baltimore-Washington area. The Krieger School of Arts and Sciences, the Whiting School of Engineering, the School of Education and the Carey Business School are based at the Homewood campus in northern Baltimore. The schools of Medicine, Public Health, and Nursing share a campus in east Baltimore with The Johns Hopkins Hospital. The Peabody Institute, a leading professional school of music, is located on Mount Vernon Place in downtown Bal...timore. The Paul H. Nitze School of Advanced International Studies is located in Washington's Dupont Circle area.