The Kalbasi laboratory at Stanford University is recruiting a post-doctoral scholar for independent research in the area of cancer immunology and T-cell based immunotherapy. The funded proposal utilizes synthetic biology tools to understand how T cell intrinsic responses to common gamma chain signaling shape in vivo anti-tumor efficacy of tumor-specific T cells. The work involves in vivo (mouse) and in vitro models of T cell therapy, single cell computational approaches, and advanced microscopy / image analysis to achieve both basic and translational goals. Further details of the proposal will be provided after initial inquiry.
The Kalbasi laboratory is a translational laboratory with an interest in advancing the treatment of solid tumors, with a disease emphasis on sarcoma. The lab is actively seeking approaches to overcome immunotherapy resistance due to T cell-intrinsic, myeloid-intrinsic and tumor-intrinsic factors. The lab also has vested interest in understanding the immunologic basis of response and resistance to radiation therapy, a widely used therapeutic tool in sarcoma and cancer care. Strengths of the Kalbasi lab include extensive experience with models to study cancer-immune interactions, access to and experience with synthetic biology tools, expertise in biology related to T cells, myeloid cells, sarcoma and radiation therapy, and access to relevant clinical samples.
Stanford is a leader in the care of patients with sarcoma, with a vibrant sarcoma research environment that spans basic, translational and clinical work. The Kalbasi lab is housed within the Department of Radiation Oncology within the Stanford School of Medicine, and is part of the Stanford Cancer Institute and is also affiliated with the Parker Institute for Cancer Immunotherapy.
This position requires a Ph.D. with a background in immunology. Additional experience in cancer biology, computational biology, and/or molecular biology is highly desirable.
Start Date: December 1, 2022
Specific Responsibilities include: experimental design, data acquisition, data processing, statistical computation, methods development, data interpretation, literature review and manuscript/grant preparation.
Additional Duties: - Supervision of undergraduates, graduate students and new trainees in the lab. - Ability to work on multiple projects efficiently and effectively - Ability to work independently on scientific projects - Assist with preparation of grant proposals - Preparation of manuscripts for publication in scientific journals - Required to communicate well with other scientists worldwide - Candidate should have 3+ years research experience in immunology; additional background in computational biology, cancer biology, and/or molecular biology preferred - Experience in image processing and analysis also preferred - The candidate will report directly to the Principal Investigator and will successfully carry out experiments and analyze the data generated with minimal supervision. - Ability to handle several projects simultaneously. - Willing to help and train various personnel in computational tools and make significant contributions to the design and execution of other laboratory members' experiments.
PhD and/or MD degree conferred prior to start date
Fluency in both spoken and written English
Applicants must be able to work in a diverse, multidisciplinary, and collaborative research environment
Required Application Materials:
Cover letter describing the candidate's relevant experience, goals and expectations for the position, and preferred start date
Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.
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Located between San Francisco and San Jose in the heart of Silicon Valley, Stanford University is recognized as one of the world's leading research and teaching institutions. Leland and Jane Stanford founded the University to "promote the public welfare by exercising an influence on behalf of humanity and civilization." Stanford opened its doors in 1891, and more than a century later, it remains dedicated to finding solutions to the great challenges of the day and to preparing students for leadership in a complex world. The University's thriving diverse community is comprised of nearly 7000 undergraduate students, 12000 graduate students, 2000 faculty members, 1900 postdoctoral scholars, and over 11,000 academic and administrative staff in seven schools including several interdisciplinary research centers and institutes. The campus spreads over 8000 contiguous acres and nearly all undergraduates live on campus. Stanford offers bachelor's and master's degrees in addition to doctoral degrees (PhD, MD, DMA and JD) plus a number of professional and continuing education programs and certifications. More at http://facts.stanford.edu and http://www.stanford.edu. Stanford is an equal empl...oyment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stanford also welcomes applications from others who would bring additional dimensions to the University’s research, teaching and clinical missions.