Position for highly motivated Assistant Professional Researcher is available with the Program in Craniofacial Biology, and Institute for Human Genetics, at the University of California, San Francisco. Candidate will be hosted in a highly interactive, collaborative, and friendly laboratory with emphasis on mentorship and personal growth.
We study the epigenetic and transcriptional regulation of morphogenesis in development, evolution, and disease. To this end, we use genome-wide, systems-level approaches, leveraging the strengths of different organismal systems, including mouse, chick, and human embryos. A special focus is on organogenesis of the craniofacial & appendicular skeleton.
Candidate will be expected to carry out specific experiments at the laboratory bench to enable the broader mission of the lab. These studies will include basic molecular biology techniques, multi-omics approaches such as RNA-seq, scRNA-seq, ATAC-seq and ChIP-seq on embryonic tissue samples, assistance in characterization of mouse mutant phenotypes including lineage tracing, RNAScope, imaging by confocal microscopy. These experimental approaches will require the candidate to be highly engaged and proactive in a dynamic research environment and in a highly collaborative atmosphere.
Candidate will be responsible for overall mouse colony management, monitoring cage counts and breeding schemes.
Candidate will be expected to advise and train post docs and other scientific members (e.g., collaborating faculty labs at UCSF and other institutions) on complex scientific techniques, e.g., CRISPR CAS9.
PhD required in genetics, developmental biology, molecular biology, biochemistry, or relevant field and postdoctoral experience following completion of the PhD, utilizing techniques or methods in developmental biology, genetics, and genomics; or an equivalent combination of education and experience;
Advanced knowledge of laboratory practices and safety;
General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications;
Excellent verbal and written communication skills and ability to interact productively with lab and campus personnel;
Ability to manage multiple tasks effectively and work under deadlines with general guidance;
Excellent organizational and planning skills to accurately complete detailed work;
Mouse husbandry and large mouse colony management experience; and
Highly Preferred Qualifications
Research experience in genomics and next generation sequencing strongly preferred.
Prior hands-on experience in genomic technologies including RNA-seq, scRNA-seq, ATAC-seq and ChIP-seq, CRISPR-Cas is highly valued and preferred.
Familiarity using mouse models including dissections of embryos at early gestational days and tissue collection and tissue specimen processing (preservation, cryosectioning, staining, imaging) will also be highly valued.
Bioinformatic skills highly desirable.
About UCSF The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.
Pride Values UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.
In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu.
Join us to find a rewarding career contributing to improving healthcare worldwide.
Please apply online at: https://aprecruit.ucsf.edu/JPF04029 with CV, Statement of Research, and contact information for three references. Applicant materials must list current qualifications upon submission. The selected candidate must meet the qualifications at the time of application.
Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.