We are seeking a creative scientist with a background in computational biology and microbiology to work on a genomics analysis-based antibiotic discovery project. The successful applicant will join a team of talented researchers at the Antimicrobial Discovery Center. Several drug lead candidates came out of our lab - ADEP (Conlon et al., Nature 2013); teixobactin (Ling et al., Nature 2015); darobactin (Imai et al., Nature 2019; Hundeep et al., Nature 2021), hygromycin A (Leimer et al., Cell 2021). Our findings show that there is a great opportunity to speed up discovery by introducing genomics-based computational approaches to identify both superior analogs of novel compounds we discovered, and novel ones based on pattern and network analysis of biosynthetic gene clusters. The computational project is a collaboration with Marnix Medema, the developer of antiSMASH, and Doug Mitchell, developer of RRE-Finder.
A strong record of publications in computational biology is an essential requirement. Familiarity with biosynthetic gene clusters is a plus. The appointment will be for a minimum of 2 years with possible extension, starting immediately. Competitive salary commensurate with experience, and a package of benefits.
Assist in initiating, executing, and completing clinical research and experiments
Prepare and write research papers, presentations, grant proposals, etc.
Train graduate students
Northeastern University is an equal opportunity employer, seeking to recruit and support a broadly diverse community of faculty and staff. Northeastern values and celebrates diversity in all its forms and strives to foster an inclusive culture built on respect that affirms inter-group relations and builds cohesion.
All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, religion, color, national origin, age, sex, sexual orientation, disability status, or any other characteristic protected by applicable law.
Founded in 1898, Northeastern University is a private research university located in the heart of Boston. Northeastern is a leader in worldwide experiential learning, urban engagement, and interdisciplinary research that meets global and societal needs. Our broad mix of experience-based education programs?our signature cooperative education program, as well as student research, service learning, and global learning?build the connections that enable students to transform their lives. The University offers a comprehensive range of undergraduate and graduate programs leading to degrees through the doctorate in nine colleges and schools.