In addition to applying for this position online, Interested candidates should contact Dr. Santhi Ganesh, Division of Cardiovascular Medicine, Department of Internal Medicine, with current resume or CV and references. Email: firstname.lastname@example.org Lab website: www.ganeshlab.org
The Ganesh lab is seeking talented Postdoctoral Research Fellow candidates for human genetics studies of vascular disease. We are conducting gene discovery studies using genome sequencing, GWAS and transcript expression profiling methods to understand both common and rare vascular diseases, including fibromuscular dysplasia, arterial dissections, arterial aneurysms, and hypertension.
To study the functional consequence of discovered genetic variation, we are using in vitro cellular and in vivo models. Our studies are closely tied to the clinic, with human tissue and blood samples from patients and thus trainees can expect to gain exposure to translational aspects of their research projects as well. We have several data sets and reagents already generated (exome sequencing, GWAS genotyping, cellular and mouse models) that provide a rich opportunity for productivity and publications for a highly motivated postdoctoral fellow. The lab is initiating a project on Neurofibromatosis and vascular disease involvement, with a well established biorepository of clinical and genetic data. We additionally are studying sex differences of the genetic findings and have preliminary data to support a project focused on this aspect as well.
Candidates should have experience and/or publications in genetics, molecular biology, vascular biology, or computational biology/transcriptomics areas, with an interest in human genetics. This is an excellent opportunity for individuals interested in both human genetics and functional biology investigations, and, to see how the two are integrated in disease-oriented research. The ideal candidate is highly motivated to learn scientific methods and to write manuscripts and grant applications. The laboratory has secured multiple NIH and non-NIH sources of funding. Dr. Ganesh is a faculty mentor of several NIH-supported T32 training grants at University of Michigan.
M.D. or Ph.D. required. Basic science discipline preferred, such as molecular biology, cell biology, or vascular biology. Candidates with computational skills are also encouraged to apply.
40 hours, full-time. Days -- hours negotiable.
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