Berkeley Lab's Joint Genome Institute (JGI) is looking for a talented Postdoctoral Fellow to join their Genome-encoded Biomaterials Group led by Dr. Crysten Blaby-Haas!
Dual-purpose technologies that supply economically viable products and mitigate anthropogenic climate change are desperately needed. A promising and versatile solution is to leverage the natural capabilities of microalgae and cyanobacteria. By converting solar energy into chemical energy, these photosynthetic microbes naturally capture carbon dioxide from the air and convert this greenhouse gas into organic compounds. These organic compounds, in turn, are the building blocks for natural and synthetic biomaterials. However, progress toward developing photosynthetic microbes as chassis for nano(bio)material synthesis is thwarted by biological complexities limiting the reliable expression of recombinant pathways. As a result, synthetic biology is largely confined to simple model organisms, such as the yeast Saccharomyces cerevisiae and the bacterium Escherichia coli. Unlike these heterotrophs that require expensive carbon inputs, such as sugars, algae naturally capture carbon from the air. However, innovative approaches are needed to break technical barriers and exploit microalgae for synthetic bioproduct formation.
In this exciting role, you will spearhead a define-with-SynBio project that aims to delineate genomic principles underlying the expression of native and non-native pathways in eukaryotic microalgae.
What You Will Do:
Generate combinatorial DNA libraries
Perform microalgal transformations and high-throughput screening
Use NGS-based functional genomics technologies to understand the regulation of recombinant genes
Design, synthesize, and clone synthetic gene clusters
Analyze data and report findings in peer-reviewed scientific journals and at conferences
Work independently and as a member of interdisciplinary research teams
Interact with internal and external collaborators
What is Required:
A recent Ph.D. in Molecular Biology, Microbiology, Biochemistry, or a related field.
Demonstrated knowledge of genome engineering, chromatin, DNA assembly, and handling microbial cultures.
Experience in molecular genetics in eukaryotes, preferably green algae.
Experience developing and implementing NGS-based functional genomics or high-throughput screening technologies.
Excellent oral and written communication skills including the ability to efficiently organize technical information for publication and presentation.
Demonstrated interpersonal skills including the ability to interact with diverse technical and scientific staff within a dynamic and collaborative interdisciplinary team environment.
What We Prefer:
Experience with high-throughput assay development and laboratory automation systems (liquid handlers, robotic colony pickers etc).
Familiarity with analyzing NGS data.
Experience in working with combinatorial DNA libraries.
Experience working with biomaterials.
For full consideration, please apply by October 15, 2022 with the following application materials:
Cover Letter - Describe your interest in this position and the relevance of your background.
Curriculum Vitae (CV) or Resume.
This is a full time, exempt from overtime pay (monthly paid), 2 year appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds, and ongoing operational needs. You must have less than 3 years of paid postdoctoral experience.
This position is represented by a union for collective bargaining purposes with predetermined postdoctoral step rates dependent on years of experience post-degree.
Salary is commensurate with experience.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
This position will be performed on site at Lawrence Berkeley National Lab, 1 Cyclotron Road, Berkeley, CA.
Learn About Us:
Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 14 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
The JGI's mission is to provide the global research community with access to the most advanced integrative genome science capabilities in support of the DOE"s research mission to solve the world's evolving energy and environmental challenges. The JGI supports projects in genome sequencing, synthesis, transcriptomics, metabolomics, and natural products in plants, fungi, algae, and microorganisms.
Berkeley Lab's Postdoc Program is committed to providing Postdoctoral Researchers and Visiting scholars with a positive and impactful experience to jump-start their career through premium research and career development, networking opportunities, mentoring programs, and a strong community. For more information, please visit our Berkeley Lab Postdoc Resources site and our Berkeley Lab Postdoc Association site.
Based on University of California Policy - SARS-CoV-2 (COVID-19) Vaccination Program and U.S Federal Government requirements, Berkeley Lab requires that all members of our community obtain the COVID-19 vaccine as soon as they are eligible. As a condition of employment at Berkeley Lab, all Covered Individuals must Participate in the COVID-19 Vaccination Program by providing proof of Full Vaccination or submitting a request for Exception or Deferral. Visit covid.lbl.gov for more information.
Berkeley Lab is an Equal Opportunity and Affirmative Action Employer. We heartily welcome applications from women, minorities, veterans, and all who would contribute to the Lab's mission of leading scientific discovery, inclusion, and professionalism. In support of our diverse global community, all qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.