Indiana University Purdue University Indianpolis (IUPUI)
Location: Bloomington, Indiana
Internal Number: 11385
Location: IU School of Medicine
Department: IUSM - Medical & Molecular Genetics
Campus: IU School of Medicine Indianapolis
The Department of Medical and Molecular Genetics at Indiana University School of Medicine is seeking applicants at the Postdoctoral Appointee level to study neuron/glia interactions using human pluripotent stem cells. Of particular interest is how these interactions are adversely affected in neurodegenerative disease states including Alzheimer's disease and glaucoma, as well as the cellular pathways that become dysfunctional, leading to neurodegeneration. An example of recent work from the lab includes:
· VanderWall KB et al. (2020), Retinal ganglion cells with a glaucoma OPTN mutation exhibit neurodegenerative phenotypes when derived from three-dimensional retinal organoids, Stem Cell Reports, 15(1): 52-66
· Fligor CM et al. (2021), Extension of retinofugal projections in an assembled model of human pluripotent stem cell-derived organoids, Stem Cell Reports, S2213-6711(21)00260-5. doi: 10.1016/j.stemcr.2021.05.009.
As the nation's largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.
The successful candidates must have a Ph.D. degree with a strong research background in stem cell biology, neurodegeneration, or neurobiochemistry. Experience with CRISPR/Cas9 gene editing or bioinformatic analyses are highly preferred, as well as candidates with strong cell culture experience in general. Candidates should also have strong communication skills in both oral presentation and writing, and be capable of working independently but could also contribute to a larger team project. Candidates will also play a role in the mentorship of graduate students and/or fellows in basic and translational research. It is highly desirable for the holder of this position to develop research projects with strong potential for long-term NIH funding, with the expectation that the candidate will also submit fellowship applications and/or research grants to eventually support at least some of their research.
Department Contact for Questions:
For questions about the position please contact: Jason S. Meyer, PhD
About Indiana University Purdue University Indianpolis (IUPUI)
IUPUI, a partnership between Indiana and Purdue universities, is Indiana’s urban research and academic health sciences campus.
IUPUI’s mission is to advance the state of Indiana and the intellectual growth of its citizens to the highest levels nationally and internationally through research and creative activity, teaching and learning, and civic engagement.
By offering a distinctive range of bachelor’s, master’s, professional, and Ph.D. degrees, IUPUI promotes the educational, cultural, and economic development of central Indiana and beyond through innovative collaborations, external partnerships, and a strong commitment to diversity.