Career Center

The Neuroimaging Genomics Laboratory, co-led by Drs. Andrew Saykin and Kwangsik Nho of the Indiana University School of Medicine Center for Neuroimaging (CfN), has immediate full-time openings for one or more outstanding, highly motivated post-doctoral research fellows with special interest in human genomics/computational systems biology to work on the genetics of Alzheimer's disease and related disorders (ADRD) using state-of-the-science integrative approaches to analyze multi-omics data. The Lab's overarching goals are 1) to achieve a better understanding of the complex causes and mechanisms leading to ADRD, 2) to improve early detection and longitudinal monitoring by combining genomics, fluid biomarkers and advanced neuroimaging and 3) to identify novel targets for diagnostic use and therapeutic intervention.

Fellows will work on research problems using rich data sets and leading-edge analytic approaches supported by multiple NIH grants (R, U and P programs). Topics include (a) human genetics of ADRD using quantitative endophenotypes from neuroimaging and other biomarkers, (b) systems biology analysis of pathways from multi-omics data using multi-layered network approaches, © machine learning for identification of genetic risk factors in ADRD, (d) relation of central and peripheral omics to ADRD biomarkers and clinical measures, and (e) studies in diverse multiethnic populations to broaden our understanding of genetics and ADRD biomarkers. Fellows will take the lead in preparing manuscripts for publication and contribute to grant applications while collaborating on other projects as part of a multidisciplinary team science effort. Special opportunities afforded by this fellowship include experience working with the Genetics Core of the Alzheimer's Disease Neuroimaging Initiative (ADNI), Indiana Alzheimer's Disease Research Center (IADRC), IU Network Science Institute (IUNI), and multiple NIH sponsored multicenter programs including the Alzheimer's Disease Genetics Consortium (ADGC), Alzheimer's Disease Sequencing Project (ADSP), Artificial Intelligence for Alzheimer's Disease (AI4AD), Alzheimer's Disease Metabolomics Consortium (ADMC), Accelerating Medicines Partnership Program for Alzheimer's disease (AMP-AD), and Model Organism Development & Evaluation for Late-Onset Alzheimer's disease (MODEL-AD).

Application Instructions

Applicants must currently reside in the U.S. and/or be eligible to begin work in the U.S. Review of applicants will continue until the positions are filled. Please email a cover letter with a brief description of research experience, interests and goals, full CV, and contact information for three references to Dr. Kwangsik Nho (knho@iu.edu).

Indiana University is a multi-campus public research institution and a world leader in professional, medical, and technological education with an annual operating budget of $2.1 billion. The Indiana University School of Medicine (IUSM) is annually ranked among the top medical schools in the nation by U.S. News & World Report. IU School of Medicine is the largest medical school in the United States and offers high-quality medical education, access to leading medical research and rich campus life in nine different Indiana cities, including rural and urban locations consistently recognized for livability.

As the nation's largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.

The IUSM had over $446 million in grants awarded for fiscal year 2020-2021, the majority of which come from the NIH. Additionally, IUSM provides an interdisciplinary, collaborative, and interactive scientific environment with many multidisciplinary centers and state-of-the-art core facilities. IUSM's clinical partner, IU Health, operates an organized system of care across 18 hospitals that offers unmatched potential for clinical, educational, and research collaborations.

The CfN is a highly multidisciplinary environment with PhD and MD/PhD students in Medical Neuroscience, Medical and Molecular Genetics and Computer Science/Bioinformatics (https://medicine.iu.edu/radiology/research/neuroimaging).

Doctorate degree is required. Successful applicants will have strong academic preparation (PhD, MD, or MD/PhD in a relevant discipline), high motivation and enthusiasm for research, excellent written and oral communication skills including evidence of successful manuscript writing and publication productivity, strong intellectual curiosity, creativity, flexibility, a commitment to the scientific goals of the program, desire to make a contribution, and the ability to work independently and as part of a collaborative transdisciplinary team, which includes mentoring graduate and undergraduate students. Preference will be given to candidates with experience in one or more of the following areas: human genetics, multi-omics data analysis including RNA-Seq, and systems biology/network analysis. Strong data science skills are required. Applicants who have recently completed their terminal degree and plan to develop an independent research career are especially encouraged to apply. Applications from groups underrepresented in biomedical research are strongly encouraged to apply.

Carla Ewing
Mgr, Human Resources & Academic Administration
Department of Radiology & Imaging Sciences