Anticipated start: As soon as possible after initial review of the applications.
Position duration: Initial appointment will be for one year. Reappointment may be considered contingent upon the availability of work and appropriate funding.
Open date: July 5th, 2022
Most recent review date: Thursday, Aug 4, 2022 at 11:59pm (Pacific Time) Applications received after this date will be reviewed by the search committee if the position has not yet been filled.
Final date: Thursday, Dec 22, 2022 at 11:59pm (Pacific Time) Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
The UC Santa Cruz Genomics Institute Organized Research Unit at the University of California, Santa Cruz (UCSC) invites applications for the position of Stem Cell Models Research Specialist in the Haussler-Salama Lab. Under the direction of Professor Sofie Salama, the research specialist will support and contribute to research that uses human and non-human primate pluripotent stem cells and high throughput sequencing assays to understand the evolution and function of genomic innovations that drive new gene regulatory programs and human brain development and disease. This work will involve using genetic engineering to generate pluripotent stem cell lines that allow CRISPR/Cas9 based overexpression or knockdown screens, or enable expression of fluorescent reporters, optogenetic actuators or calcium sensors in a cell-type specific manner. Engineered cell lines will be used for generating pluripotent stem cell derived cerebral cortex organoids for phenotypic characterization using immunohistochemistry and high throughput sequencing-based measurements. The candidate will also make scholarly contributions to the research program through reading primary literature, participate in the preparation and/or editing scientific manuscripts and regular lab meeting presentations. In addition to supporting and contributing to research, the incumbent will support our Live Cell Genomics Center and UCSC-UCSF braingeneers projects with lab operations support including assisting with ordering, reimbursement and spending reports, maintaining inventories, scheduling meetings, and communications. The candidate will be expected to learn new techniques and implement protocols, have strong attention to detail, strong written and verbal communication skills, exercise good time management and problem-solving skills, and work effectively in a team environment.
Applicants with expertise in any of the following areas are strongly encouraged to apply: pluripotent stem cell culture, CRISPR/Cas9-based genetic engineering, cerebral cortex organoid culture and analysis including histology analysis of tissue sections, and/or high throughput sequencing-based gene expression analysis.
The hiring unit will not sponsor employment-eligible immigration statuses for this position.
At least two years of biological wet lab experience including mammalian cell culture and molecular biology experiments. Experience must be obtained after award of the Bachelors degree (or equivalent foreign degree).
Curriculum Vitae - Your most recently updated C.V.
Cover Letter - Letter that summarizes in detail your qualifications, interest in the position, and your experience in the following areas:
a. With CRISPR/Cal9 gene editing b. With pluripotent stem cell culture and differentiation c. With high throughput sequencing d. Supporting lab operations (ordering, budgets, chemical inventory, hazardous waste disposal and related functions)
3 letters of reference required
Applications must include confidential letters of recommendation*. Note that your references, or dossier service, will submit their confidential letters directly to the UC Recruit System.
*All letters will be treated as confidential per University of California policy and California state law. For any reference letter provided via a third party (i.e., dossier service, career center), direct the author to UCSCs confidentiality statement at http://apo.ucsc.edu/confstm.htm. Apply link:https://recruit.ucsc.edu/JPF01335
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. UC Santa Cruz is committed to excellence through diversity and strives to establish a climate that welcomes, celebrates, and promotes respect for the contributions of all students and employees. Inquiries regarding the Universitys equal employment opportunity policies may be directed to the Office for Diversity, Equity, and Inclusion at the University of California, Santa Cruz, CA 95064 or by phone at (831) 459-2686.
Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain UCSC positions funded by federal contracts or sub-contracts require the selected candidate to pass an E-Verify check (see https://www.uscis.gov/e-verify). The university sponsors employment-based visas for nonresidents who are offered academic appointments at UC Santa Cruz (see https://apo.ucsc.edu/policy/capm/102.530.html).
UCSC is a smoke & tobacco-free campus.
If you need accommodation due to a disability, please contact Disability Management Services at firstname.lastname@example.org (831) 459-4602.
UCSC is committed to addressing the spousal and partner employment needs of our candidates and employees. As part of this commitment, our institution is a member of the Northern California Higher Education Recruitment Consortium (NorCal HERC). Visit the NorCal HERC website at https://www.hercjobs.org/regions/higher-ed-careers-northern-california/ to search for open positions within a commutable distance of our institution.
As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy.All Covered Individuals under the policy must provide proof of Full Vaccination or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, and/or Religious Objection) or Deferral (based on pregnancy) no later than the applicable deadline. New University of California employees should refer to Appendix F, Section II.C. of the policy for applicable deadlines. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements. Additional information and resources for compliance are located on the campus COVID-19 Vaccines webpage.