Berkeley Lab's Environmental Genomics & Systems Biology (EGSB) Division is looking for a Secondary Metabolite Research Scientist to leverage unique resources in fabricated ecosystems, plant genetics, metabolomics, sequencing, and gene synthesis at the Lab to gain critical new insights into the molecular mechanisms of secondary metabolites in plant-microbe-environment interactions.
What You Will Do:
Lead campaigns for the characterization of secondary metabolites.
Discover new biological roles for metabolites especially those mediating plant and microbial interactions or impacting plant growth.
Conduct biological studies using fabricated ecosystems to understand the phenotypic effects of secondary metabolites.
Use transcriptomic analysis to understand biotic and abiotic controls on secondary metabolite production.
Perform analysis of metabolomics and other systems biology data sets to gain insights into secondary metabolite biosynthesis and activities.
Provide implementation plans that include timeline, procedures, expected outcomes, and risks.
Lead cross-team and cross-group collaborative projects.
Direct the work of technical support staff.
Help prepare progress reports and proposals.
Present at international conferences and publish in high-impact, peer-reviewed journals.
Create periodic reports for the principal investigators.
Maintain appropriate records and manage data to ensure accessibility and replication of work.
Lead group meetings.
What is Required:
A minimum of 3 years of relevant experience beyond the highest customary degree in Biology or a related discipline.
Experience using integrative approaches, including metabolomics, genetics (esp. QTL analysis and Genome-Wide Association Studies), transcriptomics, genomics, bioinformatics for specialized metabolic pathway gene discovery and characterization in plants.
Demonstrated ability to characterize genes responsible for plant specialized metabolism (esp. P450s).
Experience developing genome edited plants with CRISPR/Cas9 techniques and genotyping mutant plants.
Detailed experience in plant tissue culture and transformation.
Experience working with Brachypodium distachyon esp. to study plant microbe interactions and secondary metabolite production.
Specific experience measuring antimicrobial effects of plant specialized metabolites on soil bacteria and fungi.
Experience bioengineering specialized metabolic pathways in heterologous systems (e.g. E.coli and N. benthamiana).
Expertise characterizing the effects of abiotic and biotic stress on secondary metabolite production.
Expertise in quantitative and quantitative metabolomics using both GC-MS and LC-MS c).
Experience purifying small molecules from plant tissues for NMR analysis.
Specific experience using fabricated ecosystems for plant microbiome studies.
Experience performing field and greenhouse experiments.
Expertise in analyses of systems biology data.
Demonstrated interpersonal skills including the ability to establish relationships and collaborate with a diverse interdisciplinary research team.
Excellent oral and written communication skills including the ability to present technical reports, prepare research for publication and funding for proposals.
What We Prefer:
PhD in Biology or a related discipline.
Postdoctoral Fellow experience in studying plant microbe interactions.
For full consideration, please apply by August 10, 2022 with the following application materials:
Cover Letter - Describe your interest in this position and the relevance of your background.
Curriculum Vitae (CV) or Resume.
This is a full time, exempt from overtime pay (monthly paid), 2 year Career Track Term appointment with the possibility of renewal up to a maximum of 5 years total or conversion to Career based upon satisfactory job performance, continuing availability of funds, and ongoing operational needs.
Salary is commensurate with experience.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Work will be performed onsite at Lawrence Berkeley National Lab, 1 Cyclotron Road, Berkeley, CA.
Learn About Us:
Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
Working at Berkeley Lab has many rewards including a competitive compensation program, excellent health and welfare programs, a retirement program that is second to none, and outstanding development opportunities. To view information about the many rewards that are offered at Berkeley Lab- Click Here.
Based on University of California Policy - SARS-CoV-2 (COVID-19) Vaccination Program and U.S Federal Government requirements, Berkeley Lab requires that all members of our community obtain the COVID-19 vaccine as soon as they are eligible. As a condition of employment at Berkeley Lab, all Covered Individuals must Participate in the COVID-19 Vaccination Program by providing proof that vaccination requirements have been met or submitting a request for Exception or Deferral. Visit covid.lbl.gov for more information.
Berkeley Lab is an Equal Opportunity and Affirmative Action Employer. We heartily welcome applications from women, minorities, veterans, and all who would contribute to the Lab's mission of leading scientific discovery, inclusion, and professionalism. In support of our diverse global community, all qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.