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Posted: 17-Jun-22
Location: St. Louis, Missouri
Type: Full-time
Salary: Open
Internal Number: JR67564
Scheduled Hours
40Position Summary
Job Description
Position Summary
The Rauchman (wet lab) and Dietmann labs (bioinformatics) are looking for a post-doctoral fellow to work on a collaborative project investigating epigenetic mechanisms in kidney development and disease. The project will explore how chromatin remodeling complexes (NuRD and SWI/SNF) and tissue restricted transcription factors cooperatively regulate cell fate decisions during formation of the nephron and in regenerating epithelia after injury. The main focus of our work is in understanding 1) the mechanistic basis of congenital anomalies of the kidney and 2) defining the epigenetic changes that determine healthy vs. diseased cell states in the adult kidney. To address these questions, we use a multi-omics approach that integrates single cell technologies, chromatin profiling and conformation capture methods (CUT&RUN, Hi-ChIP), spatial transcriptomics and Cas9-mediated epigenetic editing. Studies are conducted primarily in mouse models and primary cells; key findings will be validated in human samples. The opportunity will provide training and mentoring in genomic techniques (Rauchman lab) and computational biology (Dietmann lab) in a collaborative and collegial environment.
Information on being a postdoc at Washington University in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/.
Required Qualifications
Ph.D., M.D. or equivalent terminal or doctoral degree.
Preferred Qualifications
- Experience in bioinformatics.
- Interest in further developing computational skills in parallel with learning wet lab genomic techniques.
- Ability to guide research projects and maintain detailed records of experimental work.
- Background in or strong desire to learn developmental biology and epigenomics.
- Ability to work collaboratively with other members of the research group.
- Excellent oral and written communication skills.
Working Conditions
This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.
Salary Range
Base pay is commensurate with experience.
Applicant Special Instructions
Please send a cover letter and CV to Dr. Michael Rauchman at mrauchma@wustl.edu.
Required Qualifications
Ph.D., M.D. or equivalent terminal or doctoral degree.
Grade
ZSalary Range
$54,840.00 - $54,840.00 / AnnuallyThe salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.Accommodation
If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.Benefits Statement
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.EEO/AA Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the Universityâ™s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.Diversity Statement
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment â“ fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.Applicant Instructions
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