The Silva-Fisher Lab is seeking a postdoctoral researcher to work on RNA Cancer Biology of cancer metastasis. The overall researchÂ focusÂ is to study the basic mechanisms of regulatory RNAs including non-protein coding genes called long non-coding RNAs (lncRNAs) to target them and use them for new cancer treatments. The Silva-Fisher lab consists of a bioinformatics dry lab and a wet lab that work together as a team to identify and characterize mechanisms of long non-coding RNAs in metastatic cancer. Research projects include: 1) defining the mechanisms of metastatic progression, 2) understanding how lncRNA-protein interactions promote tumor growth, 3) evaluating RNA modifications in cancer, and 4) assessing the contribution of long non-coding regulation in drug response and treatment resistance. Visit https://Silvafisherlab.comto read recent publications.
The postdoctoral researcher will have the opportunity to work with Dr. Jessica Silva-Fisher, the Breast Cancer Research Program, Multiple Myeloma Group, and Single Cell RNA Sequencing Group. In addition to high-quality research facilities, career and professional development training for postdoctoral researchers is provided by Dr. Silva-Fisher and through the Mentorship to Enhance Diversity Program, Career Center, Teaching Center, Office of Postdoctoral Affairs, and campus groups. Dr. Silva-Fisher will also work closely with the postdoctoral researcher to develop an Independent Research Plan for their career development.
Trains under the supervision of a faculty mentor including (but not limited to):
Manages their own project, which should lead to a first author publication.
Develops expertise in RNA cancer biology techniques including cell culture, RNA isolation, qPCR, in vitro assays assessing (proliferation, apoptosis, and metastasis), cloning, and experience with mice.
Develops proficiency in career skills, including writing, public speaking, networking, and critical evaluation of scientific literature.
Presents scientific work both inside and outside the university with excellent oral communication skills.
Assists with grant preparation and reporting.
Prepares and submits papers on research with excellent writing skills.
Designs research experiments.
Evaluates research findings and reports results.
Manages conscientious discharge of research responsibilities.
Maintains conformity with ethical standards in research.
Maintains compliance with good laboratory practice including the maintenance of adequate research records.
Engages in open and timely discussion with mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
Performs with appropriate collegial conduct towards co-trainees, staff members and members of the research group.
Adheres to all applicable university policies, procedures and regulations. All data, research records and materials and other intellectual property generated in university laboratories remain the property of the university.
Performs as a mentor to trainees in the lab.
Ph.D., M.D. or equivalent terminal or doctoral degree.
Ph.D. in biochemistry and molecular biology, biomedical sciences, cancer biology, cancer genetics or genomics.
Background in molecular or cellular biology or RNA biology or genetics.Â
Experience working in a wet lab setting with background in RNA biology, molecular and cellular biology, including techniques such as cell culture, RNA isolation, qPCR, cloning, in vitro assays assessing (proliferation, apoptosis, and metastasis), flow cytometry, and experience with mice.
Demonstrated ability to implement laboratory procedures, conduct research and records findings.
Independent, self-motivated and eager to acquire new knowledge and skills on a regular basis.
Ability to analyze, interpret, and communicate results with others.
This position works in a laboratory environment with potential exposure to biological and chemical hazards.Â The individual must be physically able to wear protective equipment and to provide standard care to research animals.
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All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.
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Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.