Postdoctoral Scientist - Li Lab - Computational Biomedicine
Cedars-Sinai Medical Center
Location: Los Angeles, California
Internal Number: HRC0819647A
Principal Investigator, Ruowang Li, PhD, is looking for a Postdoctoral Scientist to join the Department of Computational Biomedicine!
The Department of Computational Biomedicine reflects Cedars-Sinai's commitment to advancing medical discovery and the recognition of the foundational role complex data plays in our research and clinical care. We are recruiting multiple postdoctoral research fellows in the newly established Department of Computational Biomedicine at the Cedars Sinai Medical Center (CSMC). We welcome applications from highly motivated candidates who enjoy innovative thinking. Including a cover letter and publication examples are preferred, but not required.
Are you ready to be a part of breakthrough research?
The Postdoc will join the research group of Dr. Ruowang Li and is expected to collaborate with investigators within and beyond Cedars-Sinai Medical Center. The Postdoc will work at the intersection of Biomedical Informatics, Human Genetics, and Machine Learning/Statistical Modeling. The main areas of research include, but are not limited to, methods development in constructing new polygenic risk scores (PRS) that can model higher-order complexities and improve transferability across different populations, in integrating data of large-scale population-level data, e.g., biobank-linked electronic health record data (EHR), in identifying causal effects through mendelian randomization analysis.
The group has extensive experience in working with biobank-linked EHR and PRS (Li. et al. Nature Reviews Genetics, 2021), data integration (Li. et al. Nature Communication, 2021; Ritchie. et al. Nature Reviews Genetics, 2015), and biomedical informatics (Li. et al. JAMIA 2019a, 2019b). The fellow will have access to a number of large-scale datasets, including up to five million of not-previously-analyzed patients' records in the CSMC systems. This unique opportunity provides the Postdoc the ability to perform highly original and innovative research.
Working independently but in close cooperation and in consultation with Dr. Li and other Research scientists, the Postdoctoral Scientist will perform routine and complex computational, mathematical, and statistical procedures throughout the training period. As a Postdoctoral Scientist, you may develop, adapt, and implement new research techniques, and protocols, as well as analyze, interpret, summarize, and compile data.
Primary Duties and Responsibilities:
May lead the development of new methodologies under the supervision of the mentor.
May participate in publications and presentations as author or co-author.
Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator.
Analyzes, interprets, summarizes, and compiles data.
Develops, adapts, and implements new research techniques and protocols.
May assist in the preparation of grant proposals, but is not responsible for generating grant funds.
Operates and maintains equipment and instruments.
Minimum of a Doctoral degree in Biomedical Informatics, Bioinformatics, Biostatistics, Computer Science, Data Science, or a related quantitative field, required.
Experience and Skills:
Previous experience in related research is preferred but not required.
Independently works on research projects designed in collaboration with one or more mentors within an area of specialization.
Acquires thorough technical and theoretical knowledge of research projects and objectives during one to five (1-5) year post-doctoral appointment.
Strong computing skills (R and Python) are desired.
Excellent communication skills and a good track record of writing scientific papers.
Knowledge of safety standards and maintenance of specialized equipment.
Working Title: Postdoctoral Scientist - Li Lab - Computational Biomedicine
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.