Are you ready for change? Join our multifaceted Molecular Diagnostics Laboratory Team within the Department of Pathology. We apply next-generation sequencing techniques to characterize the spectrum of genetic mutations in patient tumors. These genomic data guide treatment decisions and the enrollment of patients onto clinical trials of novel targeted therapies.
The Computational Biologist will provide bioinformatics support in developing next-generation sequencing applications to characterize the spectrum and clinical significance of genetic mutations in human tumors. You will create and use existing software and database systems to track experimental parameters, catalyze technology development, and analyze next-generation sequence data.
Design, develop and operate computational pipelines to analyze next-generation sequencing data.
Analyze data sets to discover and annotate cancer-causing genetic mutations in tumor specimens.
Evaluate the performance of novel technology platforms and assays
Collaborate with research groups to analyze biomedical data and address scientific problems with bioinformatics techniques and tools
Train researchers in the use of computational and bioinformatics tools
Develop, refine, and improve bioinformatics tools to interpret sizeable genomic data sets.
Evaluate and test third-party software packages.
Track specimen information, experimental and analysis parameters, performance metrics, and genomic results in databases
Manage and archive large data sets from next-generation sequencing experiments
Participate in the establishment and maintenance of a Laboratory Information Management System (LIMS)
Install and maintain software and data
Maintain detailed records of all analysis
Present results and progress updates at lab meetings and lead presentations to experimental and scientific collaborators
Attend seminars, lectures, and training courses to learn new computational biology skills to remain up to date with the cancer genomics field and learn new programming languages or techniques as necessary.
2-4 years of Next-generation sequencing and cancer genetics experience will be considered.
Cross-disciplinary and strong analytical skills
Experience using computational methods, databases, software, and hardware.
As one of the world's premier cancer centers, Memorial Sloan-Kettering Cancer Center is committed to exceptional patient care, leading-edge research, and superb educational programs. The close collaboration between our physicians and scientists is one of our unique strengths, enabling us to provide patients with the best care available today as we work to discover more effective strategies to prevent, control, and ultimately cure cancer in the future. Our education programs train future physicians and scientists, and the knowledge and experience they gain at Memorial Sloan-Kettering has an impact on cancer treatment and the biomedical research agenda around the world.