5600 scientists working on over 300 discovery programs in 8 disease areas focusing on 90 new molecular entities makes Novartis the premier place to develop your career as a pharmaceutical professional. If you are curious, scientifically minded, and want to positively impact society by speeding delivery of novel therapies to patients, then look no further, NIBR is the place to be. As a Scientist in the Translational Medicine PK Sciences Bioanalytical group, you will have the opportunity to make a difference. If you have a collaborative nature, a commitment to teamwork across an organization and a relentless focus on improving patient care we want you to apply.
In this laboratory-based Scientist role, you will apply your hands-on expertise to the bioanalysis of small and large molecule therapeutics, including gene therapies, cell therapies, antibody-drug conjugates, bi-trispecific/ScFV antibodies, oligonucleotides/siRNA, proteins and peptides. You will work with an elite team of scientists involved in the development and qualification of small and large molecule assays supporting pharmacokinetic, pharmacodynamic and immunogenicity studies across all phases of the drug discovery & development pipeline. Additionally, you will contribute to new technology platform evaluations to improve support for challenging new therapeutic modalities.
Your main responsibilities will include but are not limited to:
* Independently design, develop, qualify and implement bioanalytical ligand binding assays (LBAs) and qPCR (polymerase chain reaction) assays for PK, TK, PD and ADA assessment supporting various modalities such as biologics, oligonucleotides and cell and gene therapy platforms. * Deliver high quality data within defined timelines and aligned to current industry expectations. * Complete study sample analysis and draft the bioanalytical report in support of urgent project requests. * Represent the bioanalytical function on project teams and present results, data interpretation, timelines etc. at project team meetings * Collaborate with internal and external stakeholders to evaluate new bioanalytical technologies and solutions to support challenging project requests