Research Opportunities - Pulmonary & Critical Care Medicine
Washington University in St. Louis
Location: St. Louis, Missouri
Internal Number: JR65839
This opportunity will conduct research as a scientist or post-doctoral position in a lung biology lab investigating the cell biology of airway epithelial cells in human disease. Current scientific questions address the structure and function of ciliated airway cells, dysfunction in genetic diseases, including primary ciliary dyskinesia and acquired disease, such as asthma and chronic obstructive pulmonary disease. Methodologies commonly used include: primary tissue culture, microscopy, analysis of gene expression at the protein and RNA levels, and genetic manipulation. Our laboratory models human genetic disorders in the nematode, C. elegans. The ultimate goal of our research is to better understand the disease and develop therapeutic strategies for treatment. We utilize well-established genetic tools and cutting-edge high-throughput technology to identify genetic and chemical modifiers that alter disease outcome.Â
Candidates should be able to conduct relevant literature searches, develop and troubleshoot protocols, and provide technical and procedural improvements. In addition, this opportunity is in an environment with a strong teamwork culture and collaborative efforts, which requires excellent interpersonal skills.
This position works in a laboratory environment with potential exposure to biological and chemical hazards.Â The individual must be physically able to wear protective equipment and to provide standard care to research animals. In addition, human tissue and mouse models are used.Â
Proficiency in basic molecular biology techniques, including DNA, RNA, Protein isolation and purification; PCR, reverse transcription PCR, Immunoblot, ELISA.
Experience with microscopy (dissection, compound, confocal, EM).
Working knowledge of Microsoft Office, Excel, Photoshop, and Prism.
Demonstrated ability to work independently and communicate effectively, including verbal, written, and interpersonal skills.
Perform troubleshooting strategies.
Ability to maintain complete and organized records.
Working knowledge of computer software and general lab equipment.
Ability to prioritize workload.
Candidates with prior experience in molecular biology, biochemistry, genetics and/or cell biology with at least a bachelorâ™s degree are encouraged to apply.
Base pay is commensurate with experience.The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.
Washington University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration without regard to an individualâ™s sex, race, color, religion, age, disability status, protected veteran status, national or ethnic origin, gender identity or expression, sexual orientation. Women, minorities, protected veterans and the disabled are strongly encouraged to apply.
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment â“ fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.
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Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.