The laboratories of Dr. Alison Taylor and Dr. Fatemeh Momen-Heravi at Columbia University Herbert Irving Comprehensive Cancer Center (HICCC) are seeking an enthusiastic and exceptionally motivated postdoctoral research scientist for a joint project between the Taylor and Momen-Heravi laboratories on cancer genomics and transcriptomics. Applicants will be mentored by Dr. Alison Taylor and Dr. Fatemeh Momen-Heravi.
In this project, we will study the biologic determinants of cancer disparities through the lens of genomic and transcriptomic changes. Successful candidates will have a strong interest in the analysis of large-scale genetic datasets with the ultimate goal of discovering novel cancer drivers. The position will involve developing methods and pipelines for analysis of whole genome sequencing, transcriptome sequencing, chromosomal alterations (aneuploidy), and DNA copy number analysis. Prior experience with one or more of these data types is required.
Candidates should hold a PhD in computer science, bioinformatics, engineering, or a related field, and have experience in computational biology. In addition to technical and scientific knowledge, this individual should have excellent organizational and interpersonal skills, the ability to perform meticulous record keeping, and thrive in a collaborative and multi- disciplinary research setting.
The successful candidate will be highly motivated and collaborative with strong communication skills, and should have the desire to interface both with other computational/quantitative biologists and functional biologists. Applicants should have proficiency and substantial programming experience in R and/or Python.
Specific duties will include:
Deployment of existing programs and algorithms for analysis of next-generation sequencing data in support of multiple projects.
Development and maintenance of pipelines for analysis of next-generation sequencing data
Maintenance/stewardship of large-scale datasets generated by the laboratory.
Genomic/transcriptomic discovery of novel somatic alterations that drive cancer and the potential for developing independent projects in this area.
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.