To apply, please email curriculum vitae, names and contact information of three references, and a letter stating research interests to Dr. Dinesh Pal (dineshp@med.umich.edu), Assistant Professor, Department of Anesthesiology, University of Michigan.
A Postdoctoral position is available to study the neurochemical mechanisms of anesthetic-induced unconsciousness and sleep-anesthesia interfaces in rat. The postdoctoral trainee will lead the studies to investigate the mechanistic underpinnings of interactions between sleep homeostasis and sedation. The trainee will have the opportunity to work in a highly collaborative and collegial environment and will be supported by active mentoring and any additional training required for the successful completion of the project and career advancement.
The successful candidate is expected to lead the studies that may involve intracranial microdialysis in freely moving rats, HPLC quantification of neurotransmitter levels, electrophysiological sleep-wake recordings, immunohistochemical (and/or fluorescence) staining of frozen brain sections, and/or biochemical/molecular biology assays to investigate changes at enzymatic, protein, and gene expression levels.
The applicant should have a Ph.D. or equivalent degree in sleep neurobiology/behavioral neuroscience and a proven track record of productivity as evident through published research articles.
Working knowledge and prior experience with rodent stereotactic survival surgery, electroencephalography, and microdialysis/microinjections is preferred but not required. Proficiency or prior experience in analyzing sleep-wake recordings, immunofluorescent staining in frozen brain sections, high-performance liquid chromatography, cell biology and biochemistry, and/or Opto- and pharmacogenetics is highly desirable.
The successful applicant is expected to have excellent oral and written communication skills, and a strong enthusiasm for learning and developing new experimental approaches.
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