Postdoctoral Associate - Chemical & Biomolecular Engineering
Location: Houston, TX, United States,
Internal Number: 915
There is a postdoctoral research position available at Rice University in the research group of Professor Xue Gao in Chemical and Biomolecular Engineering. The job mainly focuses on developing the genome editing tools based on CRISPR technologies, through rational design and engineering of CRISPR proteins for further applications in synthetic biology nucleic acid biosensing and disease treatment applications. The job requires experience with cell biology, molecular biology, and biochemistry, including molecular cloning, protein evolution, and screening, mammalian cell culturing, CRISPR genome editing, etc. Background knowledge in human genetic diseases, gene therapy, and viral delivery is strongly preferred.
This position is hiring between $48,000 and $58,000 per year.
The George R. Brown School of Engineering ranks among the top 20 undergraduate engineering programs (US News & World Report) and is strongly committed to nurturing the aspirations of faculty, staff, and students in an inclusive environment
We seek the greater representation of women, minorities, people with disabilities, and veterans in disciplines in which they have historically been underrepresented; to attract international students from a wider range of countries and backgrounds; to accelerate progress in building a faculty and staff who are diverse in background and thought, and we support an inclusive environment that fosters interaction and understanding within our diverse community.
Rice University is an Equal Opportunity Employer with a commitment to diversity at all levels and considers for employment qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national or ethnic origin, genetic information, disability, or protected veteran status.
Leads research on engineering CRISPR genome editing tools to perform high precision genomic modifications and reduce off-target editing activities
Leads research on genome engineering projects on human genetic diseases and CRISPR-Cas protein engineering
Designs and engineers viral vectors
Explores delivery CRISPR genome editors to human primary cell lines
Develops lab research protocol SOPs related to genome editing
Documents, analyzes, and maintains research data
Assists with proposal development to obtain research funding
Mentors, oversees, and/or trains junior research team members
Supports project management and collaboration across institutions or disciplines
Provides academic services (i.e., teaching classes) to the department as required
Performs all other duties as assigned
Ph.D. or other doctoral degree in biology, bioengineering, biochemistry, or related field
No experience required
Proficiency in genomic engineering of mammalian cells
Proficiency in molecular cloning, protein expression, and purification
Expertise in biochemical assays
Expertise in RNA biochemistry and protein-DNA/RNA interaction
Proficiency in using pymol
Proficiency in protein purification and engineering for genome editing and nucleic acid detection
Familiarity with viral vector design and production
Familiarity with protein mutagenesis evolution and screening
Ability to lead junior researchers, problem-solving, and troubleshooting
Ability to write clear, concise reports, and communicate findings
Ability to work both independently and as part of a team
No substitutions for education or experience allowed
Candidates with experience in one or more of the following research areas is strongly preferred:
3D organoid culture
Creating and screening mutagenesis library
Developing high precision and multiplexed genome editing tool
Genomic and transcriptomic sequencing data processing
Rice University is an Equal Opportunity Employer with commitment to diversity at all levels, and considers for employment qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national or ethnic origin, genetic information, disability or protected veteran status.
Current Rice University COVID policies, which include vaccination, face mask, testing, gatherings, occupancy limits, and travel policies can be found here: https://coronavirus.rice.edu/policies
As a leading research university with a distinctive commitment to undergraduate education, Rice University aspires to pathbreaking research, unsurpassed teaching and contributions to the betterment of our world. It seeks to fulfill this mission by cultivating a diverse community of learning and discovery that produces leaders across the spectrum of human endeavor.