110+ clinical studies, developing novel Biomarkers using diverse and innovative technologies, global and dynamic team driving operational innovation for an outstanding impact on clinical development.
The Biomarker Development department (BMD) in NIBR Translational Medicine delivers coordinated biomarker plans using diverse expertise and knowledge in genetics, genomics, imaging, protein and cellular biology, human tissue research, vendor scientific monitoring, statistics, bioinformatics, digital endpoints, patient centric sampling and study coordination.
As a Senior Expert Imaging in the Clinical Imaging team you will actively provide strategic, scientific, technical and operational leadership on the optimal use of imaging in drug development. Be part of an imaging department with deep expertise in structural and molecular biomarkers and their application in clinical and translational development. You will interact with clinical trial teams to establish the role of imaging endpoints along novel biological mechanisms across diverse therapeutic areas. The role offers a wide view of molecules across various stages as they transition from research, to early development and subsequently to P2-3 trials. As a part of building imaging endpoints, the role also provides unique exposure to variety of other critical biomarkers (soluble and genetics) for an integrated view of identifying unique patient populations and novel readouts of efficacy and safety.
Major accountabilities include: * Act as an internal expert in PET/SPECT and Molecular Imaging with focus on clinical trials * Partner with Global Drug Development, Translational Medicine and DA Research to develop and lead "fit for purpose" in-life molecular imaging solutions * Collaborate with research to develop and lead translational imaging * Drive molecular imaging and ligand development from late pre-clinic to clinic * implement Imaging in clinical trials to add critical insights on efficacy, safety, mechanism of action * Execute imaging readouts in imaging trials using internal operational support and external contract research organizations; * Ensure quality and timely execution of imaging trials to deliver critical drug development decisions; be agile and responsive to clinical teams during the course of design , execution and interpretation of imaging trials. * Develop and manage network of external experts; be able to synthesize optimal inputs and customize for specific protocols. * Act as BMD point of contact in clinical trial teams and be able to address other biomarkers or direct to other key subject matter experts * Identify and/or develop novel imaging techniques and implement in clinical trials