The goals of the Geisler laboratory in the Department of Neurology are to gain insights into molecular mechanisms of axon degeneration in peripheral neuropathies and to develop effective treatments. We discovered that chemotherapeutics with distinct mechanisms of action converge on a common axon degeneration pathway and developed a gene therapy approach targeting this pathway. The person in this position will assist with developing and conducting research projects pertaining to gene therapy and mechanisms of axon degeneration and help with manuscripts and grant applications in the field of peripheral neuropathies.
This position assists in developing and conducting research projects, including experimental design, data analysis and documentation of experimental results.
Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data.
Performs small animal procedures, including behavioral testing, drug applications, sectioning, staining, imaging and analysis.Â
Performs tissue culture experiments, including preparation of solutions, imaging, and western blots.
Performs molecular biology experiments, including PCR, qRT-PCR, cloning, mini and maxi preps, and lentivirus generation.
Assists with grant preparation and reporting.
Performs complex statistical analysis of data collected and writes interpretative reports. Verifies the correctness of the data submitted and makes recommendations based on these analyses.
Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers.
Solves practical problems relating to difficulties with equipment or test subjects.Â Suggests technical or procedural improvements in testing methods.
Conducts literature searches related to research project.
Assures compliance with established safety procedures and maintains required documentation on laboratory and specimen conditions.
Assists with general lab maintenance and ordering.
This position works in a laboratory environment with potential exposure to biological and chemical hazards.Â The individual must be physically able to wear protective equipment and to provide standard care to research animals.
Strong knowledge and experience with mouse and rat experiments, including behavioral testing, tissue processing/analysis and work with viral vectors.
Strong initiative and troubleshooting abilities
Analytical, reasoning and problem-solving skills.
Ability to analyze and interpret statistical data and to communicate data in a clear, concise manner.Â
Computer literacy, including the ability to use a variety of software packages to analyze data.
Masterâ™s degree with four years of experience in research lab operations or an equivalent combination of education and experience equaling nine years.
$44,700.00 - $81,200.00 / AnnuallyThe salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.
Washington University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration without regard to an individualâ™s sex, race, color, religion, age, disability status, protected veteran status, national or ethnic origin, gender identity or expression, sexual orientation. Women, minorities, protected veterans and the disabled are strongly encouraged to apply.
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment â“ fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.
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