Postdoctoral Scientist - Goodridge Lab - Regenerative Medicine Institute
Cedars-Sinai Medical Center
Location: Los Angeles, California
Internal Number: HRC0528671B
Dr. Helen Goodridge is looking for a Postdoctoral Scientist to join her research group in the Cedars-Sinai Regenerative Medicine Institute!
The Goodridge Lab studies the production of myeloid cells (neutrophils, monocytes, macrophages and DCs) and their roles in infectious and inflammatory diseases, cancer, aging and tissue regeneration, working closely with other Cedars-Sinai researchers (including the Svendsen, Chen and Hazelett groups), as well as external collaborators. In recent studies, the Goodridge Lab has defined novel pathways and mechanisms of monocyte differentiation (PMID: 25597637, 29166589), demonstrated the impact of hematopoietic aging/rejuvenation on cognitive function (PMID: 30820468), and defined immune dysregulation in severely ill COVID-19 patients (PMID: 33357411). To learn more, please visit: Goodridge Research Lab | Cedars-Sinai (cedars-sinai.edu)
The applicant should have an interest and expertise in immunology and/or hematology, with strong experience of flow cytometry, tissue culture, molecular biology (e.g. scRNA-seq, scATAC-seq, ChIP, DNA barcoding), rodent studies (e.g. adoptive transfer, bone marrow transplantation) and/or evaluation of human samples.
The postdoc will work independently under the direction of the PI (Dr. Goodridge) and cooperatively with a team of other research staff to develop one or more research projects, plan and conduct experiments, and prepare data for publication and grant proposals. The postdoc will also collaborate with other investigators, train junior lab members, participate in lab meetings, and present their research at conferences.
Primary Job Duties and Responsibilities:
Submit fellowship proposals and assisting the PI with grant proposals (but not responsible for generating grant funds).
Publish research findings as first author or co-author, and presenting at internal and external meetings.
Participate in collaborations with other investigators.
Design and perform experiments.
Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator, maintaining appropriate written and electronic records.
Develop, adapt, and implement new research techniques and protocols.
Analyze, interpret, summarize and compile data.
Perform routine and complex laboratory procedures throughout training period.
Operate and maintain equipment and instruments.
Assist with training of junior lab members.
Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization, required.
Experience and Skillset:
Highly motivated and works independently on research projects designed by a mentor (typically the PI) within area of specialization, as well as collaboratively with other researchers.
Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.
Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, analysis, operation and maintenance of specialized equipment.
Bioinformatics/computational experience would be a significant advantage.
Prior experience with cell culture (stem cell culture desirable) and rodent models is preferred.
Some experience with cellular and molecular biology techniques, flow cytometry, microscopy and immunohistochemistry is a plus.
Able and willing to perform animal husbandry and work with mouse and human tissues.
Excellent written and oral communication skills are required. Knowledge of safety standards.
Scheduling flexibility including evening, weekend and holiday rotation commitment, if necessary. Travel may be required.
Working Title: Postdoctoral Scientist - Goodridge Lab - Regenerative Medicine Institute
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.