Johns Hopkins School of Medicine seeks a Research Specialist who will work independently and make judgements using prior lab experience and scientific knowledge. Work includes interpreting and evaluating results, troubleshooting, independent decisions and training/guidance of undergraduate and graduate students. In general, the candidate will be responsible for helping to manage day-to-day lab operations and will participate in research projects by other laboratory members, including, post-doctoral fellows, laboratory technicians, undergraduate, and graduate working in the laboratory. The research specialist will also be responsible for their own experiments studying the mechanism of chemotherapeutic and immunooncologic efficacy and resistance in pancreatic cancer. Note: This position is not eligible for visa sponsorship.
Specific Duties & Responsibilities:
The Research Specialist will investigate the cellular and molecular processes that lead to chemotherapeutic efficacy and resistance in pancreatic cancer. The primary duties and responsibilities of the employee will include:
Carrying out an independent research project using pancreatic cancer organoids and molecular characterization techniques.
Responsibilities will also include establishment and expansion of organoid models of disease from pancreatic cancer patient specimens undergoing biopsy or resection at Johns Hopkins Hospital.
As expertise is gained, the ideal candidate will be able to lead in the training of graduate students and post-doctoral fellows in pancreatic organoids as a model of disease, training students to perform molecular biology experiments for their research projects, assisting with imaging and analyzing data, fully maintaining the wet lab space, as well as the following for the tissue culture research:
Maintaining lab databases of reagents (strains, plasmids, antibodies etc.)
Maintain core organoid lines
Interfaces with vendors
Ordering consumables and equipment
Upholding safety regulations
The specialist will conduct their own research project and also assist/train other members of the lab in their research projects.
Goals will be to eventually publish research from projects independently conceived and executed.
Lab Management Duties:
Supervising rotating graduate students and fellows.
Training graduate students and fellows in using organoids as a model in pancreatic cancer for both basic science and translational research.
Training in tissue culture and molecular characterization (sequencing, flow cytometry, survival assays, etc.)
Applies published research methods to current experimental work by investigating published protocols and discussing them with PI. This role will also apply research methods developed in-house.
Managing supplies, interfacing with vendors, ordering consumables and equipment, maintaining records, and upholding safety regulations for organoid research.
Maintaining and organizing the living and cryopreserved biobank of patient-derived organoid tissues and other common lab reagent collections.
Trains new lab technicians and specialists.
Machines and/or Equipment Used:
Materials, machines and/or equipment used on the job include human three-dimensional tissue culture, autoclaves, thermocyclers, balances, chemoprinting equipment, centrifuges, microscopes, fluorescent plate readers.
This position regularly interacts with vendors for price inquiries and negotiations; has independent responsibility regarding supplies and equipment, with a limited budget cap.
Minimum Qualifications (Mandatory):
Bachelor's Degree in Biology, Chemistry or related field.
One year laboratory experience performing relevant techniques.
Master's degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.
JHU Equivalency Formula: 18 graduate degree credits may substitute for one year of experience. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
Bachelor's Degree in Biology or similar.
Previous experience with and strong understanding of molecular biology, biochemistry, and microscopy and human tissue culture is strongly preferred.
Special Knowledge, Skills, and Abilities:
Excellent organizational skills are required.
Record keeping & computer skills are very important.
Knowledge of Microsoft Office.
The specialist should be competent in Excel, Powerpoint (or Keynote), Word, Illustrator, and Photoshop.
Knowledge of core bioinformatics and statistical software preferred.
Classified Title: Research Specialist Role/Level/Range: ACRP/03/MA Starting Salary Range: $33,545 - $46,095 annually (commensurate with experience) Employee group: Full Time Schedule: M-F 8-5 Exempt Status: Non-Exempt Location: School of Medicine Campus Department name: SOM Sur Cameron HPB Service Personnel area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at firstname.lastname@example.org. For TTY users, call via Maryland Relay or dial 711.
The following additional provisions may apply depending on which campus you will work. Your recruiter will advise accordingly.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
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Johns Hopkins University remains committed to its founding principle, that education for all students should be grounded in exploration and discovery. Hopkins students are challenged not just to learn but also to advance learning itself. Critical thinking, problem solving, creativity, and entrepreneurship are all encouraged and nourished in this unique educational environment. After more than 130 years, Johns Hopkins remains a world leader in both teaching and research. Faculty members and their research colleagues at the university's Applied Physics Laboratory have each year since 1979 won Johns Hopkins more federal research and development funding than any other university. The university has nine academic divisions and campuses throughout the Baltimore-Washington area. The Krieger School of Arts and Sciences, the Whiting School of Engineering, the School of Education and the Carey Business School are based at the Homewood campus in northern Baltimore. The schools of Medicine, Public Health, and Nursing share a campus in east Baltimore with The Johns Hopkins Hospital. The Peabody Institute, a leading professional school of music, is located on Mount Vernon Place in downtown Bal...timore. The Paul H. Nitze School of Advanced International Studies is located in Washington's Dupont Circle area.