Postdoctoral Research Associate - Bone & Mineral Diseases
Washington University in St. Louis
Location: St. Louis, Missouri
Internal Number: JR60619
The research interest of this lab is to elucidate the cellular and molecular mechanisms underlying pathological bone loss. Major ongoing projects include the mechanisms of host-pathogen interactions in osteomyelitis and HTLV-1 mediated bone loss. The project open for this position is a collaborative one with the Mbalaviele lab (https://bonehealth.wustl.edu/research/laboratories/mbalaviele-lab/), to study the role of the inflammasome in osteomyelitis. The approaches include the use of genetically engineered mice and pathogenic bacterial strains, histological and structural analyses (such as with microCT), confocal microscopy, and culture of primary murine and human cells.
In concert with the principal investigator, the candidate is expected to design experiments with appropriate controls and execute research protocols based on methods in the literature. The candidate is expected to work towards independence in the design and execution of research projects.
The candidate is expected to analyze results and present data at lab meetings. Participation in preparation of publications and grant proposals is also expected.
The postdoctoral researcher will have the opportunity to work directly with collaborators, initiate new collaborative relationships, establish mentoring relationships, and develop an independent project. Acquisition of technical skills new to the fellow and/or laboratory is highly encouraged to improve career development.
Ph.D., M.D. or an equivalent terminal or doctoral degree.
Highly motivated, eager and quick to learn, careful, organized, and reliable.
Ability to work independently and communicate with laboratory staff and collaborating investigators.
Strong written and oral communication skills.Â
Demonstrate computer literacy, including the ability to use a variety of software packages to store, analyze and present data (Excel, Word, PowerPoint, etc.).
Experience with bioinformatics/large datasets would be welcome.
Expertise in cell culture and molecular biology, mouse genotyping, and protein analysis (Western blot and ELISA), and FACS is helpful.
Previous microbiology experience, especially with bacterial culture and genetic manipulation would be a plus.
Experience with whole animal imaging approaches, such as bioluminescence imaging or microCT.
Experience with histology, including immunostaining and confocal microscopy would be welcome.Â
Base pay is commensurate with experience.
Applicant Special Instructions
To apply for this position, please send a cover letter and C.V. to:
The Division of Bone and Mineral Diseases at the Washington University School of Medicine is part of a dynamic multidisciplinary community of researchers dedicated to the study of local and systemic diseases affecting bone metabolism. In early 2012, the Division moved to a new space in the BJCIH as part of a Center for Musculoskeletal Research, a vibrant community of ~15 labs with complementary interests and expertise, providing a rich training environment. In addition to high-quality research facilities, career and professional development training for postdoctoral researchers at Washington University is provided through the Career Center, Teaching Center, Office of Postdoctoral Affairs, and campus groups. Additional information on being a postdoc at Washington University in St. Louis can be found at postdoc.wustl.edu/prospective-postdocs.
This position works in a laboratory environment with potential exposure to biological and chemical hazards.Â The individual must be physically able to wear protective equipment and to provide standard care to research animals.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.
Washington University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration without regard to an individualâ™s sex, race, color, religion, age, disability status, protected veteran status, national or ethnic origin, gender identity or expression, sexual orientation. Women, minorities, protected veterans and the disabled are strongly encouraged to apply.
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment â“ fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.