The Judith Sulzberger Genome Center within the Department of Systems Biology is involved with all aspects of next generation sequencing for a wide range of research projects, and is equipped with state-of-the-art high-throughput instruments. The Single Cell Analysis Core provides single-cell RNA-sequencing services and ATAC-sequencing using the 10x Genomics Chromium platform and an internally developed plate-based scRNA-seq platform. We have extensive collaborations with investigators at Columbia University and across the country and abroad, including in personal medicine and cancer genomics. Members of the lab have ample opportunities to be involved in the development of novel techniques in library preparation and sequencing.
40%: Carrying out sophisticated and cutting-edge experiments for the Single Cell Core, including but not limited to sample processing, experimental design, and planning. Provide expert technical guidance to postdoctoral researchers, and faculty.
40%: Carrying out sophisticated experiments for the NextGen Core, including but not limited to sample processing, experimental design, and planning.
10%: Managing NextSeq user base, inventory, and training of new users.
10%: Attending the laboratory needs for nextgen and single-cell cores: lab management, ordering, inventory management, financial management, IT coordination, equipment repair and maintenance, compliance, updating and maintaining research protocols, training updates, certifications.
Knowledge and understanding of the field of next-generation sequencing, in particular how this field supports the broader research of the Columbia scientific community.
Uses that knowledge to solve moderately complex problems and find new perspectives.
Interacts daily with scientists to provide technical expertise.
Able to apply analytical skills to help problem solve with senior staff associates and Director.
Judgement must be informed by analysis of multiple sources of information.
Works independently to design and execute routine projects with minimal supervision
Expected to show a medium level of initiative
Works independently to execute routine experiments while working in a collaborative research environment.
Requires a medium degree of independent judgement.
Training of technician B position in the NGS lab.
Able to identify and recommend improvements to processes and best practices for the core and its needs.
Required to implement protocols to support projects, using a comprehensive understanding of research techniques, software and instruments.
Assist collaboratively research groups, explain complex information.
Contributing in preparation of publications (manuscripts, funding proposals).
Contributes to scientific manuscripts.
Bachelor's degree in biology, biochemistry or related field.
4 years of related work experience preferred.
Columbia University is an Equal Opportunity Employer / Disability / Veteran
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.