Become a member of a vibrant research team under the direct supervision of Principal Investigator Gordon Mills, MD, PhD in the OHSU Department of Cell, Developmental and Cancer Biology. Participate in an ongoing broad research program concerning the use of combination therapies to overcome adaptive resistance in breast and gynecological cancers.
Areas of active development in Mills Lab include: selecting combinations of DNA damage repair drugs, targeting homologous repair deficiencies and/or replication stress, and identifying patterns of tumor adaptive resistance in transcriptomics and proteomics data types. Further, this position will provide opportunities to collaborate in cutting-edge clinical trials and access to patient biopsy data across omics types.
This position is for a Computational Biology and/or Bioinformatics Postdoctoral Scholar who will have the opportunity to design and lead research projects for prioritizing therapies, selecting combination therapies, and evaluating resistance pathways in breast, ovarian, and endometrial cancers. Specific duties include:
Applied computational research project(s) in precision oncology of breast and gynecological cancers.
Maintaining reproducible scripts, code, and interactive notebooks as needed for research projects, including ongoing methods documentation (i.e. maintaining a dry lab notebook or GitHub code repositories).
Participating in lab meetings, making contributions and submitting research for publication, submitting applications for research funding, presenting research at seminars, poster sessions and conferences.
Comfort with one or more of: whole exome sequencing, transcriptomics, proteomics, or single-cell data types
The ideal candidate should be self-motivated, have independent research abilities, clear communication skills, and be able to work in a team
PhD in Computational Biology/ Bioinformatics
Applied cancer biology projects
R/ Python; applied statistics knowledge
Experience in one or more of the following methods areas is strongly preferred: network/pathway analysis, network methods for drug discovery, transcriptomics and/or proteomics-based biomarker discovery, or machine learning for drug discovery
Apply here online. Please be sure to upload a cover letter and resume or CV.
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or email@example.com.
As the state's only health and research university, OHSU brings together patient care, research, education of the next generation of health care providers and scientists and community service to improve the health and well-being of all Oregonians.The university is a conduit for learning for more than 2,800 students, providing training to interns, residents and fellows in postgraduate medical and research. It is the only place in Oregon that grants doctoral degrees in medicine, dentistry and nursing. OHSU cares for more than 251,000 patients each year from around the region and takes a leadership role in contributing to solutions involving the health of the state and the nation, such as health care access and transparency, ethics and workforce shortage. Beyond providing critical health care services, quality education and cutting-edge research, OHSU also is a key economic and social force in the Northwest. With an annual operating budget of $2.06 billion and more than 14,000 employees, OHSU is Portland?s largest employer. Its size contributes to its ability to provide... many services and community support activities not found anywhere else in Oregon. For more information visit http://www.ohsu.edu/xd/about/index.cfm