Postdoctoral Scholar Parsons Lab - Regulation of Pancreatic Progenitor Cells
The Parsons Lab researches the regulation of pancreatic progenitor cells during the development and regeneration of insulin-producing ? cells. We investigate how specific progenitors are chosen following ?-cell ablation, as well as the molecular and cellular mechanisms used in regeneration. Although the cellular origins of pancreatic cancer remain enigmatic, the progenitors we study express many of the genes that mark cancer stem cells. Our research employs the zebrafish as a model system and a variety of tools, including transgenic overexpression, CRISPR mutagenesis, FACS and single-cell RNAseq. Discovering the molecular mechanisms utilized by pancreas progenitors during repair will lead to a better understanding of pancreas biology. These discoveries will impact our understanding of how to make new endogenous ? cells and the events that surround pancreatic cancer initiation.
This position is an exciting opportunity for a candidate who possesses a strong research background in stem cell biology, molecular biology, genetics and developmental biology. Good written and oral communication skills are essential, along with excellent project management skills. Familiarity with zebrafish as a model system is preferable, but not required. We will prioritize applicants with additional research experience in studying functional genomics/bioinformatics. The postdoctoral scholar should possess strong abilities to take initiative and will be expected to apply for fellowship grants as well as develop a journal article for publication.
UCI BioSci provides numerous opportunities for cross-disciplinary collaboration and opportunities for public-facing research. The Parsons Lab is committed to scientific excellence, diversity, and providing mentorship for professional and career development. For more information about our lab, please visit: https://sites.uci.edu/parsonslab/
Since 1965, the University of California, Irvine has combined the strengths of a major research university with the bounty of an incomparable Southern California location. UCI's unyielding commitment to rigorous academics, cutting-edge research, and leadership and character development makes the campus a driving force for innovation and discovery that serves our local, national and global communities.