The Pomerantz laboratory is looking for an enthusiastic, motivated individual to join as Associate Specialist. The laboratory studies basic and translational aspects of tissue regeneration, and its research program is closely related to regenerative medicine. With foundations in muscle and cancer biology, we are investigating natural regenerative mechanisms such as stem cell function and de-differentiation. By employing model organisms such as zebrafish and mouse, and extending discoveries to human cells and tissues, we focus on fundamental insights that can be translated into clinical advances, most notably solving congenital or acquired structural and reconstructive problems of the limbs, face and head.
This position will involve the study of skeletal muscle regeneration and stem cell biology. The incumbent will isolate stem and progenitor cells from human muscle biopsies and will study gene expression patterns at the single cell level. The incumbent will also study human muscle stem cell in vivo after transplantation into animals, and in vitro differentiation properties. The selected candidate will also study regeneration of volumetric muscle defects, using a combination of cells and agents such as hydrogel. The selected candidate will participate in research projects involving regeneration of limb, body and craniofacial tissues. Finally, this position will involve participation in grant and manuscript writing and preparation, along with recurring presentation of the incumbent's findings internally and at external conferences and meetings.
Required qualifications: • A master's degree (or equivalent degree) or at least five years of experience in the relevant specialization. • Previous experience in working with mice. • Direct experience performing single cell RNA-sequencing and single cell ATAC-sequencing. • Direct experience with the following techniques: histology, immunohistochemistry, western blot analyses, flow cytometry, microscopy, cell culture. • Ability to organize data and keep detailed records. • Excellent communication skills (both oral and written) in English. • Flexibility and willingness to work on multiple projects.
Preferred qualifications: • Extensive knowledge of craniofacial development, signaling pathways, muscle stem cell homeostasis. • Experience working on translational research projects. • Excellent organization skill and attention to detail. • Excellent time and task management skills. • Ability to work effectively in a team environment. • Ability to work independently. • Strong analytical abilities and problem solving skills. • Ability to maintain comprehensive laboratory notebook of experiments done on a daily basis. • Ability to work independently and assess need for assistance from supervisor. • Post-graduate training in field.
Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service. Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary will be commensurate with the applicants experience and training.
UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.