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Postdoctoral Associate - Proteomics
Weill Institute for Cell and Molecular Biology
The Yu laboratory (http://www.yulab.org/) is large research group in the Weill Institute for Cell and Molecular Biology thatperforms research in the broad area of Network Systems Biology with both high-throughput experimental (see Vo et al., Cell 2016; Tippens et al., Nature Genetics, 2020) and integrative computational (see Wang et al., Nature Biotechnology 2012; Kumar et al., Nature Methods, 2020) methodologies, aiming to understand gene functions and their relationships within complex molecular networks (protein-protein interactome and gene regulatory networks in particular) and how perturbations to such systems may lead to various human diseases. Representative publications from the lab can be found below.
An experimental ("wet-lab") position is available to develop proteomics technologies and carry out large-scale functional proteomics projects (we have a lab-owned state-of-art Thermo Fusion Lumos machine). The ideal candidate should have a strong track record and extensive lab experience in molecular biology, biochemistry, cell biology, and/or genetics. Experience with protein biochemistry (i.e., cloning, purification, co-immunoprecipitation, etc.) and mass spectrometry is strongly preferred. Experience in network biology or systems biology is not required.
How to Apply:
The starting date is flexible and can be as early as Fall 2021. Applications will be accepted until the position is filled. Competitive salary commensurate with experience and skills, as well as a generous benefits package will be offered. Interested applicants should send a PDF with CV, a brief description of future research interests (optional), and contact information for three references to Dr. Haiyuan Yu (firstname.lastname@example.org). Please include "Yu Lab Postdoc 2021" in the subject line. Informal inquiries are welcome.
Transcription imparts architecture, function, and logic to enhancer units, Nature Genetics, 2020
An interactome perturbation framework prioritizes damaging missense mutations for developmental
disorders, Nature Genetics, 2018
A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to
Human, Cell, 2016.
A Massively Parallel Pipeline to Clone DNA Variants and Examine Molecular Phenotypes of Human
Disease Mutations, PLoS Genetics, 2014.
Integrative annotation of variants from 1,092 humans: application to cancer genomics, Science, 2013.
Three-dimensional reconstruction of protein networks provides insight into human genetic disease,
Nature Biotechnology, 2012.
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Internal Number: JOB_POSTING-3-38772
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