The Bandopadhayay Laboratory (www.bandolab.org) based at the Dana-Farber Cancer Institute and Broad Institute seeks a bioinformatics analyst to join in efforts to develop and apply cutting-edge genomic technologies to determine optimal treatment strategies for children with brain tumors.?? This research associate will be co-mentored by our collaborator Dr. Rameen Beroukhim (www.beroukhimlab.org) and will be involved in cross-disciplinary efforts to generate large datasets describing genetic changes across pediatric brain tumors and other cancers, and to develop and apply sophisticated statistical and computational approaches to analyzing these data. These datasets include DNA sequencing, RNA sequencing and epigenetic sequencing, both at bulk and single-cell level. The aim of these efforts will be to characterize mutations that cause pediatric brain tumors and to determine how to treat patients with these cancers.
The ideal candidate will have extensive programming ability and a strong background in mathematics and statistics with a deep interest and background in biology.?? The ability to collaborate closely with other members of a research team is essential.
Interprets complex biological information. Performs tasks to reduce and consolidate output from software. Prepares data for utilization by other scientists.
Monitors new data from public databases, finds and loads missed data, cleans loaded data to satisfy quality control criteria.
Must be able to query various sources for the information needed; i.e., the Web, publications and internal DFCI resources.
Directs and guides DNA, RNA and protein sequence database searches and the computational analysis of resulting data.
Implements end-users needs in database searching and integration.
Maintains the computational infrastructure and controls the flow of samples and information for large-scale studies.??
Recognizes and reports problems with the data management process and fixes the problems whenever possible.
Apply existing analytic algorithms to large genomic datasets.
Work with researchers and computational biologists to develop and code new algorithms
Interact with users and other stakeholders to determine and prioritize requirements.
Bachelor???s degree required
A strong background in programming, preferably in R or MATLAB
Excellent written and verbal communications skills.
Self-starter with excellent problem-solving, organizational, and people skills.
A strong interest and background in biology is preferred.
Exposure to an analytic field such as bioinformatics, computational biology, machine learning, or statistics is preferred.
A minimum two-year commitment is required
Bando Lab Mission and Culture
Who we are and what we do
We are a team of scientists who are dedicated to applying cutting edge methods and technologies to find better treatments for children with brain tumors. We are united in our mission to work as hard as we can, together as a team, and collaboratively with researchers in other programs, to find those treatments that are so desperately needed for thousands of children diagnosed with brain tumors around the world.
Diversity is essential in science and medicine
We, the members of the Bando Lab, want to make the following statement concerning equality in the workplace. Our lab celebrates diversity, and we recognize that our team only stands to gain from including members with different backgrounds, ways of life, experiences and opinions. We hold ourselves accountable for treating each other fairly and equally to create the best environment possible to succeed with our goals as researchers and individuals. Cancer does not discriminate, so to beat it, neither can we.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.
Internal Number: 2021-23872
About Dana-Farber Cancer Institute
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to under-served members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.