The Cedars-Sinai Regenerative Medicine Institute is looking for a Postdoctoral Scientist to join Dr. Ghiam's laboratory!
Under the direction of Mehrnoosh Saghizadeh Ghiam, PhD, associate professor of Biomedical Sciences at the Cedars-Sinai Board of Governors Regenerative Medicine Institute Eye Program, the Saghizadeh Ghiam Laboratory is focused on identifying specific molecular corneal defects associated with corneal pathological conditions, such as diabetes. The goal of the Saghizadeh Ghiam Lab is to understand the roles of microRNAs in both the differentiated epithelial and stem cells of normal and diabetic corneas as well as their roles in driving peripheral activation of limbal stem cells in normal and diseased corneas. To learn more, please visit: Saghizadeh Ghiam Research Lab | Cedars-Sinai (cedars-sinai.edu)
Are you ready to be a part of breakthrough research?
The candidate will be assigned to a funded project investigating the mechanism of microRNAs in limbal epithelial stem cells in rescuing vision in human organ-cultured corneas for diseased corneas such diabetic and limbal stem cell deficiency. The work will involve the use of stem cells, tissue and organ-cultured cornea, transfection, luciferase assays, QPCR, histological and molecular analysis of samples with the overall goal of translation of the approach to the clinic. In order to conduct this research the incumbent should have a primary interest in regenerative medicine, experience in the fields of visual neuroscience and/or gene therapy research, technical aptitude in molecular biology, protein analysis, microscopy and histology. Working independently but in close cooperation and in consultation with the Principal Investigator and a Project Scientist, the Postdoc will perform routine and complex laboratory procedures throughout their training period. The incumbent may develop, adapt, and implement new research techniques and protocols and will analyze and interpret data.
Primary Job Duties and Responsibilities:
May assist in preparation of grant proposals, but is not responsible for generating grant funds.
May participate in publications and presentations as author or co-author.
Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the P.I.
Participation in laboratory meetings, keeping a lab notebook, performing calculations, tabulating data, summarizing methods and results of related experiments and general lab maintenance will be required.
Analyzes, interprets, summarizes and compiles data.
Operates and maintains equipment and instruments.
Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization.
Experience and Skillset:
Highly motivated and works independently on research projects designed by a mentor (typically the PI) within area of specialization.
Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.
Ability to function efficiently and cooperatively with a team of faculty, research associates, technicians and students.
Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis, and operation and maintenance of specialized equipment.
Knowledge of safety standards and maintenance of specialized equipment.
Scheduling flexibility including evening, weekend and holiday rotation commitment. Travel may be required.
Excellent written and oral communication skills are essential.
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.