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Application Review Date
The First Review Date for this job is: 6/7/2021
The Innovative Genomics Institute (IGI) is a multidisciplinary research institution focused on genome engineering and potential applications in agriculture, microbiology and biomedicine. It is a joint venture between UC Berkeley and UC San Francisco, with the administrative operations located on the Berkeley campus. This position is located at the UC Berkeley campus.
The IGI is presently seeking a talented and motivated Staff Research Associate (SRA) to conduct research towards clinical translation of genetic therapies for inherited blood disorders such as sickle cell disease, primary immunodeficiency and cancer. This work will be performed as part of a multidisciplinary team of genome engineers, stem cell biologists and immunologists at the Center for Translational Genomics (CTG) at UC Berkeley. Specific goals will be cell culture of primary and induced pluripotent stem cells, evaluation of new genome editing tools for cell therapy, the improvement of existing therapeutic approaches, and the assessment of ex vivo genome editing outcomes in human hematopoietic stem/progenitor cells (HSPCs) and/or T cells.
This position is ideal for candidates intending to pursue graduate or medical school education. The environment is exciting and fast-paced, and offers the opportunity to work at the cutting edge of genome editing and HSPC- and/or T cell-based therapies.
The incumbent will work directly with the CTG Project Scientist and other SRA staff on setting up, conducting, and analyzing results from experiments on a daily basis. They will report to the CTG Director. This position will be central in developing a robust pipeline for gene therapy work in the CTG.
?Under general supervision, perform a variety of repetitive but highly specialized laboratory experimental procedures in field of genome editing such as blood disorders like sickle cell disease, primary immunodeficiency, or cancer
Perform experiments involving lentivirus production and transduction
Execute and troubleshoot ex vivo delivery of genome editing reagents
Perform evaluation of genome editing experiments by next-gen sequencing, flow cytometry, and other assays
Modify, adapt or improve standard procedures to meet the needs of various projects
Acquire and apply skills in conducting research towards clinical translation of genetic therapies for inherited blood disorders
Strong organizational skills and attention to detail
Excellent oral and written communication skills
Experience working in a wet lab
Previous experience with
Preclinical mouse models
Tissue culture / sterile techniques
Knowledge of the development of genetic and/or cell-based therapies
Ability to keep proper industry-standard records
Ability to collaborate with researchers and work efficiently in a diverse group
Knowledge of the development and improvement of genome editing tools
B.A. or B.S. in Molecular Genetics, Cell Biology, Biochemistry, Bioengineering, or related discipline
Salary & Benefits
Salary commensurate with experience. For information on the comprehensive benefits package offered by the University visit:
Please submit your cover letter and resume as a single attachment when applying.
Equal Employment Opportunity
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status. For more information about your rights as an applicant see:
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