A postdoctoral fellow position is available in Dr. Hao Chen's lab, College of Pharmacology, University of Tennessee Health Science Center. The postdoctoral fellow will work on a NIH funded projects that studies genetic, transcriptomic, and epigenetic mechanisms of addiction-like phenotypes in rats. The primary research objective is to study the molecular mechanisms of candidate genes associated with nicotine self-administration phenotypes in rats.
The postdoc fellow will be using state-of-the-art CRISPR/Cas9 in vivo genome editing methods to selectively knockout the target genes in specific neurons in specific brain regions. In addition to studying the behavioral effects, the postdoc will also study the transcriptome changes resulting from gene knockout and nicotine self-administration. Additional studies will use state-of-the-art single nuclei RNA-seq methods to identify gene expression changes from individual cell types.
Internal Number: 218571
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