Under the supervision of the Principal Investigator, the Technician B will be responsible for carrying out fully planned experiments on genetic, epigenetic, and chemical mechanisms of neurological disorders including autism and Huntingtonâ€™s disease. They will generate, maintain, and perform experiments using cell cultures and mouse models. The technician will prepare DNA and RNA samples, perform qRT-PCR, histology, immunolabeling, and imaging using wide field microscopy and live-cell imaging techniques with training and supervision provided by the principal investigator. They will maintain colonies of transgenic mice and perform genotyping and behavioral testing and will also be responsible for ordering and maintaining laboratory supplies and the daily upkeep of the laboratory and its resources. In addition, they will provide support to projects run by postdoctoral and graduate research trainees and will perform other related duties as assigned. The technician will be expected to be detail oriented and organized and keep records of laboratory and safety documents as well as experimental data.
Carry out planned experiments to model neurodevelopmental and neurodegenerative disease: 30%
Maintain of animal colonies and genotyping: 25%
Perform behavioral assessments and tissue collection in laboratory mice: 20%
Manage laboratory operations through ordering and inventory of supplies, preparing laboratory stocks, and maintaining equipment: 15%
Performs related duties & responsibilities as assigned/requested: 10%
A Bachelorâ€™s degree in biology, chemistry, neuroscience, physics, or related science or equivalent combination of education, training and experience is required.
Proficiency with MS Word, Excel, PowerPoint, and Outlook is preferred. Six months or more experience working with laboratory rodents and/or primary cell culture is preferred. Works well independently and in a team environment.
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 514763
About Columbia University
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.