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Systems Genetics of Sleep and Circadian Rhythms in Drosophila
The Laboratory of Systems Genetics at NHLBI was established under the Earl Stadtman Investigator program, designed to facilitate high-risk, high-impact research. The research of the group and its members is supported by the collaborative and interdisciplinary NIH intramural program and state-of-the-art high-performance computing, high-throughput sequencing, proteomics, bioinformatics, and other core facilities. The laboratory uses systems genetics approaches to study genetic variation in sleep and circadian rhythms in natural populations of Drosophila. The lab is currently pursuing several projects designed to uncover the relationship between molecular polymorphisms, transcripts, and sleep phenotypes in order to understand the interaction of gene networks with environmen


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