A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
We are looking for a highly motivated PhD-trained individual for a postdoc position and team player with a strong interest in understanding the cancer biology of leukemia and early T-cell development/regeneration with a goal to develop the basic science foundation needed to improve the effectiveness and safety of current medical treatments. Please see our website for additional details: http://chiangmarky8.wix.com/chiang-lab
Specific methodologies include (but not limited to):
Transcriptional genomics (ChIP-Seq/ATAC-Seq library preparation; RNA preparation for RNA-Seq library preparation; computational analyses of sequencing data using existing pipelines; basic bioinformatics)
Transcription factor assays (reporter; CRISPRi; ChIP; gel shift; qRT-PCR)
Early T-cell development and leukemogenesis assays (flow cytometry sorting and analysis; histology; bone marrow transplantation; intrathymic injections; retroviral transduction and transplantation; in vitro stromal cell culture; transplantation in NSG mice)
Model systems include:
Genetically engineered mouse models (Cre-loxP)
Human leukemia patient-derived xenograft models
Human and mouse leukemia cell lines
Design, perform, analyze, and interpret experiments with a level of supervision from PI and other lab members in line with existing skill set with goal towards independence
Work as a team with other lab members, such as the bioinformaticist and the lab manager/work-study students who manage the mouse colony and maintain the lab
Supervise undergraduate and rotation students
Train other lab members as needed
Collaborate with members of other labs as needed
Write first-authored manuscripts for publication
Write first-authored abstracts for intramural/extramural research conferences
Generate and present posters and give talks at lab meetings, combined lab meetings, and intramural/extramural research conferences
Travel to research conferences and other labs outside the university as needed
PhD in a biomedical field
Experience in genetically engineered mouse models
or protein biochemistry
or transcription factor assays
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
The University of Michigan is an equal opportunity/affirmative action employer.
Internal Number: 197229
About University of Michigan - Ann Arbor
A great university is made so by its faculty and staff, and Michigan is recognized as one of the best universities to work for in the country. The Michigan culture is known for engaging faculty and staff in all facets of the university to create a workplace that is vibrant and stimulating.For two consecutive years, the Chronicle of Higher Education has placed U-M in its "Great Colleges to Work For" survey. In particular, the university earns high marks for strong relations between faculty and administrators, a collaborative system of governance, strong pay and benefits, and a healthy work/life balance.