Working at MIT offers opportunities, an environment, a culture - and benefits - that just aren't found together anywhere else. If you're curious, motivated, want to be part of a unique community, and help shape the future - then take a look at this opportunity.
RESEARCH SPECIALIST , Center for Biomedical Innovation (CBI) , to provide comprehensive technical support for high-throughput sequencing projects and computational analysis. CBI is conducting research related to monoclonal antibody and cell therapy manufacturing to demonstrate how real-time measurement of protein product quality attributes and rapid assessment of adventitious agent contamination can be used for manufacturers' risk-based decision making in continuous protein production, and to address key technology bottlenecks in cell therapy manufacturing for the production of safe and effective cell therapy products. Will work with research staff on the development of novel bioinformatic pipelines for rapid adventitious agent detection, developing targeted adventitious agent sequencing databases, performing in silico experiments to evaluate bioinformatic approaches, developing novel sequencing approaches using state-of-the-art sequencers (e.g., Oxford Nanopore Minion), and evaluating the capability of these approaches compared to current state-of-the-art; and assist with bioinformatic analysis of high-throughput sequencing results; perform programming to develop and modify bioinformatic algorithms; analyze large-scale quantitative data sets using statistical methodology and advise on experimental design; synthesize, interpret, and document experimental results; present results internally to research group members and externally to sponsor; publish project results through written reports, case studies, and manuscripts; and conduct relevant literature reviews and bibliographic searches for literature leads and references.
Job Requirements REQUIRED : bachelor's degree in computational biology, bioinformatics, human genomics, or related biological data science field; interdisciplinary bioinformatics research experience; knowledge of current bioinformatics trends, public genomic tools, databases, and utilities, with a focus on next-generation sequencing and genome annotation; excellent time-management, organizational, and verbal and written English communication skills; and ability to work independently and collaboratively. PREFERRED : master's degree and experience working with virus databases. Job #19536
Internal Number: 19536
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