The Bioinformatics Analyst I position is responsible for bioinformatics and computational biology in support of the Bioinformatics Specialist, Principal Investigator (PI) and lab research goals. Range of duties include, but is not limited to, writing and developing computer code, data analysis, data QC, and data management including data archiving. Performs computational approaches involved in data analysis of single cell datasets such as snmC-seq datasets. Applies computational and statistical methods for big-data analysis. As needed, provides support on programming and analysis tasks from senior level Bioinformaticians.
Bioinformatics Analysis (90%)
Perform computational data analysis on various types of datasets.
Independently write and develop software code using various coding languages for various purposes.
Perform statistical tests on large and small scale datasets.
Provide support to existing personnel for data analysis.
Testing and optimizing existing software code.
Perform QC on various types of datasets.
Interact constantly with members of the team and present progress and results.
Work effectively and efficiently work on multiple projects simultaneously.
Write detailed protocols, documentation and reports for various activities performed.
(10%) Support for lab compute infrastructure
Provide support for managing and/or performing maintenance of existing compute infrastructure
Write protocols, documentation and reports for various compute infrastructure aspects, if needed.
Typically requires a minimum of 1 year of relevant bioinformatics experience after a Bachelor’s degree.
Hands-on work experience in statistics and bioinformatics methods.
Relevant experience acquired through education and/or profession must include: proficiency in Python programming; fluency in at least 2 common programming languages (Bash, AWK, or R); next-generation sequencing technologies and assays; and high performance computing (e.g., SGE environment)
Experience communicating effectively with various levels of staff
Minimum 6 months of experience on DNA methylation datasets and/or single cell datasets
Minimum of 1 year analysis experience with NGS / High-throughput sequencing data analysis
Experience in biology
Bachelor’s degree in bioinformatics, computational biology, computer science, biological sciences, bioengineering, mathematics, statistics or related discipline.
Master’s degree in bioinformatics, computational biology, computer science, biological sciences, bioengineering, mathematics, statistics or related discipline.
SKILLS AND ABILITIES
Proven organizational and time management skills to successfully set priorities, meet established deadlines and recognize new problems with constantly changing priorities and frequent interruptions.
Strong communication skills (both verbal and written) needed to interact professionally and effectively in the work environment. Ability to read, comprehend, and discuss research materials. Proven ability to write, edit and proofread research results. Skill at explaining difficult concepts and training users and students.
Ability to interact diplomatically and professionally with all levels of Institute staff and external contacts.
Ability to identify, download, install, troubleshoot and assess new analysis tools.
Demonstrated knowledge and experience with MAC or Linux/UNIX operating systems.
Experience applying machine learning approaches for data integration and data mining.
Theoretical and practical knowledge of biological sciences (particularly genetic and molecular biology).
SPECIAL CONDITIONS OF EMPLOYMENT
Satisfactory completion of the Institute’s background investigation.
Must be willing to sign confidentiality agreement
Must be willing to work in an animal-related research environment.
Must be a U.S. Person to work on certain DoD-funded programs.
This position requires constant adjusting focus, grasping, handling, heading, keying, seeing, sitting, talking, touching/feeling, analyzing, calculating, communicating, reading, reasoning, writing, and working inside.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c)
Salk scientists are dedicated to innovative biological research. The Salk Institute consistently ranks among the leading research institutions in the world for its faculty's contributions and the impact of their findings. Focused both on discovery and on mentoring future generations of researchers, Salk scientists make groundbreaking contributions to our understanding of cancer, aging, Alzheimer's, diabetes and infectious diseases by studying neuroscience, genetics, cell and plant biology, and related disciplines. "We lead biological research. We prize discovery. Salk is where cures begin."Overlooking the Pacific Ocean in La Jolla, the Salk Institute offers a warm, collegial and collaborative work environment, where employees enjoy a generous benefits program. Social activities on campus encourage interaction as a community.