| Responsibilities: Postdoctoral fellowship positions are available immediately in the Department of Laboratory Medicine and Pathology at the University of Minnesota to investigate molecular mechanisms that regulate cardiac hypertrophy and remodeling in response to stresses. The main objective is to determine how canonical Wnt/ beta-catenin signaling interacts with TCF7L2 isoforms regulate cardiac gene expression and structural remodeling. Gene expression and epigenetic modifications will be investigated and interpreted in the context of TCF7L2 isoform recruitment. Spatial genomics and NGS will be utilized to investigate regional differences in gene expression and Wnt signaling. Data generated in genetic mouse models will be interpreted in the context of different types of failing human hearts with distinct pathologic findings. Inquires can be sent to Dr. Faqian Li at lif@umn.edu. The University of Minnesota offers a comprehensive benefits package including: · Competitive wages, paid holidays, vacation and sick leave · Low cost medical, dental, and pharmacy plans · Health care and dependent daycare flexible spending accounts · Disability and employer paid life insurance · Wellbeing program with reduced insurance premiums · Tuition reimbursement opportunities covering 75%-100% of eligible tuition · Student loan forgiveness opportunity · Opportunities for growth and promotion · Employee Assistance Program For more information regarding benefits: https://policy.umn.edu/sites/policy.umn.edu/files/appendix/postdocappoint_appa.pdf | 
