The University of Southern California (USC), founded in 1880, is located in the heart of downtown L.A. and is the largest private employer in the City of Los Angeles. As an employee of USC, you will be a part of a world-class research university and a member of the âTrojan Family," which is comprised of the faculty, students and stage that make the university what it is.
The Kuhn-Hicks Laboratory at USC Michelson Center Convergent Science Institute in Cancer (CSI-Cancer) is studying circulating tumor cells (CTCs) in the liquid biopsies (blood and bone marrow) of cancer patients as an approach to manage cancer care. Our single-cell multi-omic approach allows us to look at the morphology, proteome, and genome of these CTCs individually. Collectively, this information permits an understanding of the disease in hopes of enabling personalized medicine in oncology.
Our effort is led by a multidisciplinary team of scientists and physicians across the nation. We have multiple ongoing clinical studies to explore the utility CTCs in different cancers. We are currently searching for an energetic and passionate research technician with demonstrated knowledge and competence in various key functional areas with an emphasis on genomic technology to support our Next Generation Sequencing team. Ideal candidate will perform a variety of tasks, including isolating DNA from single cells and tissue samples, constructing libraries, performing quality control, working with a variety of microarrays, PCR, and DNA sequencing technologies. Position requires handling a great number of DNA samples and perform sequencing reactions, for many users. In addition, the qualified candidate will play a vital role in processing our research samples (mostly blood and bone marrow aspirates), along with carrying out other essential duties in the lab. The candidate will undertake a variety of laboratory procedures of technical nature, both independently and as a reliable team member.
Duties and Responsibilities:
Perform whole genome amplification and Illumina library preparation for sequencing
Maintain and calibrate genomic equipment such as bioanalyzer and qubit DNA quantification equipment
Aliquot and test kits for general use while maintaining genomic stations such as bioanalyzer, purification station, thermocyclers, and more
Maintaining and updating genomic SOPs
Demonstrates a general mastery of research/lab processes including, cell culture, sample processing.
Manage the daily operations of the lab with a high degree of independence; including overseeing timely orders of laboratory supplies, maintaining and operating equipment, and coordinating collaborative work with other researchers and service providers
Ability to problem solve and trouble shoot both technically and intellectually while understanding relevant scientific, molecular, and technical disciplines.
Communicate with lab members to prioritize tasks as needed
Perform other duties as assigned, including but notÂ limited to, immunofluorescent staining, and microscopy.
Work in a clean and sterile environment
Handle multiple (up to 96) PCR reactions at once
Work with multi-channel pipette
Read, optimize, and modify protocols on as need bases
Ability to prioritize, organize, and handle high volume/tasks workload efficiently while meeting strict deadlines.
Ability to work harmoniously with others in order to move tasks and projects forward
Work closely and report concerns and issues to supervisor.
Proficient in Microsoft Office applications (Word, Excel, PowerPoint, and Outlook).
The University reserves the right to add or change duties at any time.
***Interested individuals should provide their CV and a 1-2 page cover letter describing their professional goals and how their research experience can advance these research goals***
The ideal candidate must have the ability to organize and utilize reagents and samples for high-throughput analysis in support of genomic studies and two years proven experience in DNA sequencing, data review and stringent record keeping.
Proficiency utilizing onboard sequencer and commercial bioinformatics tools, core or service facility experience and the ability to assist in new protocol development. Experience with multiple next generation sequencing technologies including Illumina NextSeq or HiSeq is preferred.
The ideal candidate must have significant experience in a research laboratory setting with demonstrated knowledge and competency in various critical functional areas. Possess excellent interpersonal communication skills with high emphasis on collaboration, meticulous attention to details, competent at working independently, and the ability to quickly adapt to a broad scope of projects. Fully competent and proficient in the operation of sophisticated scientific equipment and independently able to perform complex procedures and techniques with accuracy
Bachelorâs degree in Biology, Molecular Biology, Biochemistry or related Biological Science area.
At least 4 years of experience working in wet laboratory setting is required
Note: A brief test will be administered to cover applicantâs knowledge of solution preparation.
Candidate will work in a high throughput laboratory providing data to senior scientists and staff researchers
Will be working with blood and tissue samples.
Must have a reliable means of transportation to retrieve packages containing biological substances at local courier facility.
Work schedule includes alternating Saturdays.
Adhere to our Environmental Health and Safety to monitor safe storage and disposal of chemicals.
Must comply with General Lab Safety, Blood Borne Pathogens.
On-site location only (no remote work).Â Â Â Â
Must be able to stand and/or sit for extended periods of time.
Must be able to carry and lift 10-20 pounds regularly.
Must be able to wear personal protective equipment (PPE) correctly throughout the day.
Required Documents and Additional Information:
Resume and cover letter required (may be uploaded as one file). Please do not submit your application without these documents.
Job openings are posted for a minimum of (5) five business days. This job may be removed from posting boards and filled any time after the minimum posting period has ended, so please apply on the same business day if interested.
The University of Southern California is an Equal Opportunity Employer that Values Diversity.
Minimum Education: Bachelor's degreeMinimum Experience: 4 yearsMinimum Field of Expertise: Degree in directly related specialized scientific field. Previous specialized laboratory experience, knowledgeable in use of specialized laboratory equipment. Working knowledge of lab procedures, techniques and testing related to specialized scientific field. Computer literacy.
USC is the leading private research university in Los Angeles—a global center for arts, technology and international business. With more than 47,500 students, we are located primarily in Los Angeles but also in various US and global satellite locations. As the largest private employer in Los Angeles, responsible for $8 billion annually in economic activity in the region, we offer the opportunity to work in a dynamic and diverse environment, in careers that span a broad spectrum of talents and skills across a variety of academic and professional schools and administrative units. As a USC employee and member of the Trojan Family—the faculty, staff, students, and alumni who make USC a great place to work—you will enjoy excellent benefits, including a variety of well-being programs designed to help individuals achieve work-life balance.