A postdoctoral fellowship is available in the Herman B Wells Center for Pediatric Research at the Indiana University School of Medicine. Our laboratory is currently exploiting the CRISPR/Cas9 system to study normal and malignant hematopoiesis. We have established an efficient system to modify genes in both human and mouse hematopoietic stem cells. Using this system, our team will focus on (1) developing gene therapy for monogenic blood disorders (Fanconi anemia, immune-deficient disorders, and hemoglobinopathies); (2) modeling activating mutations that are recurrently found in patients with hematopoietic malignancies; (3) unrevealing novel functions of Zinc finger transcription factors in hematopoiesis in vivo. We also have a close collaboration with Dr. Brian Walker on campus to discover a novel therapeutic treatment for multiple myeloma.
This position will address a postdoctoral fellow at the entry-level. The routine works will include but not limited to genetic modification of primary cells and cell lines, functional characterization of edited cells, and monitor of edited cells in vivo. The ideal candidate should familiar with cellular and molecular biology techniques. Experience in hematopoiesis and mouse handling is preferable. Willingness to work with animals is required.
As the nation's largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.
Doctorate or Terminal degree required. PhD in Molecular or Cell Biology, Physiology, or a related field and/or MD. The candidate should be able to work independently as well as direct others, design and conduct experiments, and have effective oral and written communication skills.
Department Contact for Questions:
Dr. Ngoc-Tung Tran Assistant Professor email@example.com
OAA #: IUSM010202016
Internal Number: 10575
About Indiana University Purdue University Indianpolis - IUPUI
Founded in 1820, Indiana University is the state’s public university system, comprised of two core campuses—IU-Bloomington and IUPUI—and six regional campuses located throughout the state. Combined, the total student population is more than 114,000 undergraduate, graduate and professional school students. IU is one of the largest employers in the state, with over 20,000 faculty and staff. Indiana University is an equal employment and affirmative action employer and a provider of ADA services. Diversity and inclusion remains a core commitment to IU’s mission to cultivate an educational environment that supports equal access, participation and representation on all of its campuses and that provides educational and career opportunities for all.