Under direct supervision of the Principal Investigator, perform technical support to drive scientific research in the field of pediatric neuro-oncology. Participate in supervising junior research staff and support personnel.
Independently implement technical procedures for assignments, including:
Perform genetic manipulation and genetic analysis of tumor cells (in vitro and in vivo) and supervise/train lab members in these experiments
Perform western blot, qPCR, ChIP qPCR, flow cytometry, immunohistochemistry and fluorescence microscopy of tumor slides and tumor cells and supervise/train lab members in these experiments
[Potentially] perform animal orthotopic (brain) tumor implantation surgeries; train and supervise lab members in animal experiments
Participate in formulating research methods and suggest options for improving quality
Assist other team members in their projects
Independently participate in academic authorship of manuscripts and grants related to lab work
Make recommendations on best technical approaches to investigate a scientific problem
Independently implement technical procedures for assignments
Participate in laboratory meetings
Responsible for accurate record keeping
Interact with collaborators as necessary to provide interpretation of study results
Communicate and make recommendations to other scientists in the team
Train personnel in existing laboratory techniques and procedures; explain and demonstrate technology and equipment capabilities, operation limitation and outcomes
Bachelor’s Degree in a recognized field of science directly related to the position
Minimum one year of directly related laboratory experience
Exceptional work ethic in a highly competitive environment
Ability to communicate clearly the results of his/her experiments to other team members
Working knowledge of principles in molecular biology, microbiology and immunology
Proficiency in Microsoft Word, PowerPoint, Excel, and GraphPad Prism
Familiarity with basic laboratory instrumentation and maintenance of laboratory equipment
Proficient in record keeping
A solid command of tissue culture and in conducting studies in a BSL-2 environment is necessary
A proven record in cellular and biochemical drug screening assays is required
Master’s Degree or PhD in a recognized field of science directly related to the position
Minimum three to five years’ of directly related laboratory experience
Familiarity with University research administration policies and procedures
Hands-on skills and experience in immunological, biochemical and molecular techniques including isolation of primary cells, quantification of mRNA (qPCR). cloning, and protein expression, ELISA, western blotting, biochemical and cellular screening assays
Experience with animal models and animal orthotopic (brain) tumor implantation surgeries
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
The University of Michigan is an equal opportunity/affirmative action employer.
Internal Number: 195232
About University of Michigan - Ann Arbor
A great university is made so by its faculty and staff, and Michigan is recognized as one of the best universities to work for in the country. The Michigan culture is known for engaging faculty and staff in all facets of the university to create a workplace that is vibrant and stimulating.For two consecutive years, the Chronicle of Higher Education has placed U-M in its "Great Colleges to Work For" survey. In particular, the university earns high marks for strong relations between faculty and administrators, a collaborative system of governance, strong pay and benefits, and a healthy work/life balance.