The Division of Molecular Genetics in the Department of Pediatrics is searching for a candidate to immediately participate in the conduct of studies on the molecular and cellular mechanisms of Prader-Willi syndrome, using stem cell models of human disease.
Applicant will be working in the Egli laboratory for the studies using both cells from patients with Prader-Willi syndrome and from healthy controls to study the functional significance of the differential progression of DNA replication on maternal and paternal alleles at the Prader-Willi locus. Applicant should have experience in using various techniques including the genetic modification of stem cells, directed differentiation, flow cytometry, immunocytochemistry, single molecule analysis of replicating DNA, and whole genome copy number analysis using the Saphyr Bionanogenomics instrument. The applicant will be part of an active collaborative research team, seeks input actively and develops strong communication skills. S/He will present data in talks and seminars and through the preparation of manuscripts.
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