When the work you do every single day has a crucial impact on the lives of others, every effort, every detail, and every second matters. This shared culture of happiness, passion, and dedication pulses through Cedars-Sinai, and it's just one of the many reasons we rank as one of the top hospitals in the nation by U.S. News & World Report. From working with a team of committed healthcare professionals to using state-of-the-art facilities, you'll have everything necessary do something incredible--for yourself and for others!
The Goodridge Laboratory at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for a Research Bioinformatician I to join our dynamic group. The ideal candidate should have experience in managing and analysis of large datasets using programming languages such as C/C++, Java, Perl, python, R, or the Unix(Linux) environment. The candidate should have an interest in pathways and mechanisms of immune cell production and function. To learn more, please visit: Goodridge Research Lab | Cedars-Sinai (cedars-sinai.org)
Under close supervision by the PI, project scientists, and postdoctoral scientists, as well as bioinformaticians in collaborating groups, the Research Bioinformatician I performs general bioinformatics analysis and software support for projects involving omics. The RBI will manage omic data including loading and querying data from database system and public repositories, and transform and merge multilevel omic data into user-friendly formats, assist in development, test, and maintenance of modular software pipelines, provide daily bioinformatics data analysis, preliminary interpretation of the data, and reports of the results for possible publications.
Primary Duties & Responsibilities:
Provides general bioinformatics analysis support for omic projects and mainly responsible for data analysis and software compilations including next generation sequence alignment, polymorphism identification, expression analysis, and visualization tools and browsers.
Summarizes data analyses results in the form suitable as the basis for the first draft of written reports, and makes preliminary interpretations of the data.
Assists in development, testing, and maintenance of modular software pipelines for genome sequencing, assembly, annotation, metagenomic analysis, and genotyping using high-throughput sequencing platforms including 454, Illumina, and Pacific Biosciences
Manages data including loading and querying data from database systems, downloading omic data from public repositories, and transforming data to the necessary formats
Helps to identify, evaluate, and incorporate relevant algorithms and software pipelines by reviewing pertinent literatures in bioinformatics and computational biology
Department Specific Duties and Responsibilities:
Helps develop tools and pipelines as necessary to keep pace with rapid advances in sequencing technology
Continues to learn and adapt to new analysis pipelines and software to improve research output
Educates others about bioinformatics through mentoring of and teaching colleagues, investigators, fellows, and graduate students
Works with laboratory staff to develop and implement analysis frameworks
Keeps accurate and detailed project records of experiments and results
Maintains lab equipment and related records
Maintains computer database with relevant information
Implements scripts for the analysis of complex imaging and multi-omic analysis datasets
Scheduling flexibility including evening, weekend and holiday commitment is required
Travel may be required
Bachelor's Degree in Computer Science, Electrical Engineering, Computational Biology, Bioinformatics or relevant fields required (e.g. Biology with strong quantitative training, biostatistics with concentration in bioinformatics). Master of Science degree, preferred.
Experience and Skillset:
0 - 3 years in a research environment
Background and work knowledge in algorithms, scientific computing, and machine learning or statistics
Knowledge of C/C++, Java, Perl, python, and the Unix (Linux) environment
Experience in manipulating, analyzing, and annotating very large genomic (e.g. NGS) data sets, both in exploratory and pipelined fashions, is a plus
Working Title: Research Bioinformatician I - Goodridge Lab
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.