Description: We are currently recruiting for a candidate within the Specialist series focusing on the dissection of molecular and cellular pathways underlying synaptic pruning. This person will explore novel candidates in regulating synaptic pruning in relation to mechanisms of diseases like ASD and schizophrenia, and perform translational research, building upon our previous studies (e.g. Li et al, EMBO J, 2020). This person will play a primary role in making research strategies, leading program development, designing experiments, collecting and analyzing data.
Responsibilities include, but are not limited to: • Lead one or more research projects in a dynamic and collaborative environment • Apply research grants • Make detailed observations, analyze data, interpret results and communicate clearly • Design and implement assays for the discovery and validation of novel therapeutic targets • Attend conferences, write and publish manuscripts in peer-reviewed journals
Required Qualifications: • Ph.D. in Genetics, Neurobiology. • 5+ years of postdoctoral work experience. • Experience with grant application and high-profile publication is required. • Experience in the field of GPCR and neuron-glia interaction is highly desired. • Working experience with mice is required, including mouse breeding, genotyping, dissection, stereotactic intracranial and intravitreal injection of virus. • Expertise in the culture of mammalian cell lines, primary neurons, microglia, human iPSC. • Proficiency in a broad range of molecular genetic, biochemical, and cellular techniques including: transfection, RNA interference, Western blotting, QPCR, FACS, immunofluorescence and/or live imaging techniques, immunohistochemistry, 3D-image reconstruction and quantitative image analysis. • Experience with electrophysiological recording is preferred. • Highly organized with excellent analytical and critical thinking skills. • Strong oral/written communication skills. • Knowledge of necessary lab, and data safety and security procedures and requirements. • Previous mentor experience with research assistants and students is preferred.
UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.