The main research focuses of the Nakai lab are: (1) AAV vector biology - capsid assembly, genome packaging, and virus-host interactions in rodents and non-human primates; (2) AAV antigen-antibody interactions; (3) developing novel vectors by engineering of AAV capsids; and (4) preclinical studies of gene therapy for the treatment of various human diseases. The lab takes a multidisciplinary approach to solving these problems, utilizing both wet and dry lab techniques. The lab is a part of the Human Islet Research Network (HIRN) supported by the NIH NIDDK.
The Department of Molecular and Medical Genetics at Oregon Health & Science University (OHSU) in Portland, Oregon, is seeking a highly motivated and enthusiastic Postdoctoral Scholar to study adeno-associated virus (AAV) and its application for human gene therapy in the lab led by Professor Hiroyuki Nakai, M.D., Ph.D. Specifically, the lab is looking for a post-doctoral researcher who can lead productively a newly funded NIH U01 project where we seek to develop clinically relevant novel AAV vectors and methods for in vivo regeneration of insulin-secreting beta cells in rhesus macaques and profoundly understand the mechanisms behind the technologies.
The Postdoctoral Scholar will join a multidisciplinary collaborative team and participate in global collaboration in the HIRN community, with an ultimate goal to develop AAV gene therapy for type I diabetes. The Postdoctoral Scholar will also contribute to the training of graduate, undergraduate, and high school students, as well as research staff.
Salary for this position aligns with the NIH Scale .
Substantial knowledge and skills in molecular biology
Ability to perform multiple tasks at one time
Ability to organize and handle a large quantity of samples and data
PhD in a relevant field, MD, DVM or MD/PhD
Strong enthusiasm and dedication for AAV and gene therapy research
Willingness to work on non-human primate studies
Apply here online. Please be sure to upload a cover letter and Resume or CV.
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